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The Vitreous: Structure, Function, and Pathobiology - Tapa blanda

Sebag, J.

 
9781461389101: The Vitreous: Structure, Function, and Pathobiology

Sinopsis

The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how the vitreous is composed and what role it plays in normal physiology. Over the years, however, many studies have produced independent findings concerning vitreous biochemistry, structure, and physiology. The Vitreous organizes these findings into a well-constructed compendium that not only addresses the most current scientific knowledge, but also reviews historical perspec­ tives in a manner that lends richness to the scope of the book. The first few chapters present an exhaustive, yet readable, review of the body of scientific data that have come from laboratories and researchers throughout the world. Extensive bibliographies direct interested readers further into specific aspects of the basic science of the vitreous. Chapter II: "Embryology" and Chapter IV: "Structure" present a novel organizational approach to assembling and presenting data in an integrated manner. Chapter V: "Functions" and Chapter VI: "Development and Aging" introduce fresh perspectives on the importance of the vitreous as some­ thing more than a vestigial space filler within the eye.

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Reseña del editor

The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how the vitreous is composed and what role it plays in normal physiology. Over the years, however, many studies have produced independent findings concerning vitreous biochemistry, structure, and physiology. The Vitreous organizes these findings into a well-constructed compendium that not only addresses the most current scientific knowledge, but also reviews historical perspec­ tives in a manner that lends richness to the scope of the book. The first few chapters present an exhaustive, yet readable, review of the body of scientific data that have come from laboratories and researchers throughout the world. Extensive bibliographies direct interested readers further into specific aspects of the basic science of the vitreous. Chapter II: "Embryology" and Chapter IV: "Structure" present a novel organizational approach to assembling and presenting data in an integrated manner. Chapter V: "Functions" and Chapter VI: "Development and Aging" introduce fresh perspectives on the importance of the vitreous as some­ thing more than a vestigial space filler within the eye.

Reseña del editor

The Vitreous - Structure, Function, and Pathobiology, with a foreword by C.L. Schepens, presents a comprehensive overview of the biochemical composition, molecular organization, morphologic structure, physiology, and metabolism of the vitreous body of the eye. The pathobiology of vitreous and vitreoretinal disorders is discussed within the context of derangements of normal biology and of a shared basic pathobiology. The book examines such developmental and inherited disorders as dominant exudative vitreoretinopathy and Wagner's disease; connective tissue disorders, including Marfan's syndrome and Stickler syndrome; cellular invasion through trauma, inflammation, and neoplasia; vascular invasion through trauma and the role of the vitreous in neovascularization; vitreoretinal traction; and such miscellaneous conditions as myopia, aphakia, retinitis pigmentosa, and asteroid hyalosis, as well as the effects of surgical intervention through vitrectomy, photocoagulation, cryopexy, and intravitreal injections. A novel approach to the effects of diabetes mellitus on the vitreous is offered. Clinicians will be able to use this monograph as a basic science reference manual; researchers will obtain a better understanding of the problems that confront clinicians, which should help them direct their research to the areas relevant to clinical problems that need development.

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