Protein Engineering and Design

ISBN 13: 9781420076585

Protein Engineering and Design

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9781420076585: Protein Engineering and Design

Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science.

Experimental Protein Engineering

The first half of the book discusses experimental approaches to protein engineering and starts by describing several high-throughput screening platforms for protein engineering. Key techniques used for diversity generation are also discussed. The next few chapters present examples of therapeutics, enzymes, biomaterials, and other proteins that have been engineered by rational or combinatorial approaches. The section finishes with a chapter on the use of non-natural amino acids in protein engineering.

Computational Protein Design

The second half of the book introduces computational protein design, beginning with a chapter on computational and informatics algorithms used in protein engineering. Core components of computational protein design are then discussed in detail, and examples of heuristic protein design are provided. Subsequent chapters present examples of how computational design has played a critical role in advancing the field of protein engineering. Concluding with a chapter outlining current challenges in the field, this book makes computational protein design and diversity-oriented protein engineering widely accessible to a broad audience in academia and industry alike.

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About the Author:

Sheldon Park holds a B.A. in math and physics from the University of California (Berkeley), an M.S. in physics from Massachusetts Institute of Technology, and a Ph.D. in biophysics from Harvard University. He studied protein engineering and design while working as a postdoc for Dr. Jeffery Saven and Dr. Eric Boder at the University of Pennsylvania. Since 2006, he has been a professor of chemical and biological engineering at University at Buffalo. In his research, Dr. Park uses modeling and simulation to analyze protein molecules and uses high-throughput screening to engineer protein molecules of various structure and function. He is particularly interested in developing efficient methods of engineering complex protein molecules with potential biotechnological and biomedical applications.

Jennifer Cochran holds a B.S. in biochemistry from the University of Delaware and a Ph.D. in biological chemistry from Massachusetts Institute of Technology (MIT). She studied and developed combinatorial protein engineering methods while a postdoctoral fellow in the lab of K. Dane Wittrup in the Department of Biological Engineering at MIT. Since 2005, she has been a professor of bioengineering at Stanford University. Dr. Cochran’s laboratory uses interdisciplinary approaches in chemistry, engineering, and biophysics tostudy complex biological systems and to create designer protein therapeutics and diagnostic agents for biomedical applications. She is interested in elucidating molecular details of receptor-mediated cell signaling events and at the same time developing protein and polymer-based tools that will allow manipulation of cell processes on a molecular level.

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Park, Sheldon J.
Editorial: Boca Raton, Florida, U.S.A.: CRC Pr I Llc (2009)
ISBN 10: 1420076582 ISBN 13: 9781420076585
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Descripción Boca Raton, Florida, U.S.A.: CRC Pr I Llc, 2009. Hardcover. Estado de conservación: New. Ship out 1-2 business day,Brand new,US edition, Free tracking number usually 2-4 biz days delivery to worldwide Same shipping fee with US, Canada,Europe country, Australia, item will ship out from either LA or Asia,es. Nº de ref. de la librería ABE-7815294856

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Park, Sheldon J.
ISBN 10: 1420076582 ISBN 13: 9781420076585
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Descripción 2009. HRD. Estado de conservación: New. New Book. Shipped from US within 10 to 14 business days. Established seller since 2000. Nº de ref. de la librería VT-9781420076585

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PARK, SHELDON J.; COCHRAN, JENNIFER R.
Editorial: CRC Press (2017)
ISBN 10: 1420076582 ISBN 13: 9781420076585
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Descripción CRC Press, 2017. Hardback. Estado de conservación: NEW. 9781420076585 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Print on Demand title, produced to the highest standard, and there would be a delay in dispatch of around 10 working days. Nº de ref. de la librería HTANDREE0252453

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Editorial: Taylor Francis Inc, United States (2009)
ISBN 10: 1420076582 ISBN 13: 9781420076585
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Descripción Taylor Francis Inc, United States, 2009. Hardback. Estado de conservación: New. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science. Experimental Protein Engineering The first half of the book discusses experimental approaches to protein engineering and starts by describing several high-throughput screening platforms for protein engineering. Key techniques used for diversity generation are also discussed. The next few chapters present examples of therapeutics, enzymes, biomaterials, and other proteins that have been engineered by rational or combinatorial approaches. The section finishes with a chapter on the use of non-natural amino acids in protein engineering. Computational Protein Design The second half of the book introduces computational protein design, beginning with a chapter on computational and informatics algorithms used in protein engineering. Core components of computational protein design are then discussed in detail, and examples of heuristic protein design are provided. Subsequent chapters present examples of how computational design has played a critical role in advancing the field of protein engineering. Concluding with a chapter outlining current challenges in the field, this book makes computational protein design and diversity-oriented protein engineering widely accessible to a broad audience in academia and industry alike. Nº de ref. de la librería BTE9781420076585

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Park, Sheldon J. (Edited by)/ Cochran, Jennifer R. (Edited by)
Editorial: CRC Pr I Llc (2009)
ISBN 10: 1420076582 ISBN 13: 9781420076585
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Revaluation Books
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Descripción CRC Pr I Llc, 2009. Hardcover. Estado de conservación: Brand New. 1st edition. 416 pages. 9.53x6.34x0.94 inches. In Stock. Nº de ref. de la librería __1420076582

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Editorial: CRC Press (2009)
ISBN 10: 1420076582 ISBN 13: 9781420076585
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Descripción CRC Press, 2009. Hardcover. Estado de conservación: New. Never used!. Nº de ref. de la librería P111420076582

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Sheldon J. Park
ISBN 10: 1420076582 ISBN 13: 9781420076585
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Descripción 2009. Hardcover. Estado de conservación: New. Hardcover. Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties an.Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. 402 pages. 0.739. Nº de ref. de la librería 9781420076585

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CRC Press
Editorial: CRC Press (2009)
ISBN 10: 1420076582 ISBN 13: 9781420076585
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Descripción CRC Press, 2009. Hardcover. Estado de conservación: New. 1. Ships with Tracking Number! INTERNATIONAL WORLDWIDE Shipping available. Buy with confidence, excellent customer service!. Nº de ref. de la librería 1420076582n

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