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Sinopsis
Drugs usually have no natural affinity for the cells, tissues and organs where therapeutic effects are needed, which frequently results in low efficiency and unwanted side effects. This concern is even more profound when using highly potent and cytotoxic anticancer drugs or specific agents, such as enzymes and genetic materials, since their effective and safe action requires precise cellular or even sub-cellular addressing in the target organ. To meet safety, efficiency and specificity requirements, drugs somehow must be targeted to the sites of their expected therapeutic action. The idea of the "magic bullet," or drug targeting, proposed by Erlich a century ago, generates great and continuously growing interest in biomedical, industrial and financial circles. This book is focused on the strategies designed to target therapeutic or diagnostic agents to the disease sites. In an attempt to include in this volume the set of chapters reflecting both traditional and emerging areas of drug targeting, we have contacted many leading scientists in the field asking for their contributions. Their responses were most favorable and encouraging. As a result, we have succeeded in assembling a series of outstanding contributions reflecting practically all the key areas of drug targeting. The final structure of this book is as follows.
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Reseña del editor
Drugs usually have no natural affinity for the cells, tissues and organs where therapeutic effects are needed, which frequently results in low efficiency and unwanted side effects. This concern is even more profound when using highly potent and cytotoxic anticancer drugs or specific agents, such as enzymes and genetic materials, since their effective and safe action requires precise cellular or even sub-cellular addressing in the target organ. To meet safety, efficiency and specificity requirements, drugs somehow must be targeted to the sites of their expected therapeutic action. The idea of the "magic bullet," or drug targeting, proposed by Erlich a century ago, generates great and continuously growing interest in biomedical, industrial and financial circles. This book is focused on the strategies designed to target therapeutic or diagnostic agents to the disease sites. In an attempt to include in this volume the set of chapters reflecting both traditional and emerging areas of drug targeting, we have contacted many leading scientists in the field asking for their contributions. Their responses were most favorable and encouraging. As a result, we have succeeded in assembling a series of outstanding contributions reflecting practically all the key areas of drug targeting. The final structure of this book is as follows.
Reseña del editor
This book includes general principles of drug targeting, targeting in the cardiovascular system, tumor targeting, brain targeting, miscellaneous targeting and novel approaches for targeting (new horizons). It is designed in a course-like fashion: from more general and simple to more specific and complex material. This framework will help even unfamiliar readers to learn new topics and navigate in the text. Although the book is aimed primarily at industrial and academic pharmacologists and drug discovery researchers, its design will make the book useful for advanced level graduate students. The book focuses on ligand-mediated drug targeting strategies, with additional chapters on general aspects of drug delivery that are of paramount importance in drug targeting (biological barriers, stealth technologies). Included are topics on targeting of genetic materials important in the biomedical context of the ligand-mediated targeting.
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Biomedical Aspects of Drug Targeting
Publicado por
Kluwer, USA, 2002
ISBN 10: 1402072325
ISBN 13: 9781402072321
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Hardcover. Condición: Near Fine. 1402072325. Hardcover, from closed pharmaceutical company library. Lending record shows this book has never been borrowed. 506 pages, index, illustrated with charts, tables and diagrams. Includes general principles of drug targeting, targeting in the cardiovascular system, tumor targeting, brain targeting, miscellaneous targeting and novel approaches. In a course-like fashion: from general and simple to specific and complex material. For pharmacologists and drug discovery researchers, along with advanced level graduate students. The book focuses on ligand-mediated drug targeting strategies, with additional chapters on general aspects of drug delivery that are of paramount importance in drug targeting (biological barriers, stealth technologies). Included are topics on targeting of genetic materials important in the biomedical context of the ligand-mediated targeting. Contents as new, clean, tight and bright. Book. Nº de ref. del artículo: 027082
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Biomedical Aspects of Drug Targeting
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Hardcover. Condición: Très bon. Ancien livre de bibliothèque avec équipements. Edition 2003. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 2003. Ammareal gives back up to 15% of this item's net price to charity organizations. Nº de ref. del artículo: F-979-743
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Biomedical Aspects of Drug Targeting
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Hardcover. Condición: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less 2.02. Nº de ref. del artículo: G1402072325I3N00
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Biomedical Aspects of Drug Targeting
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Biomedical Aspects of Drug Targeting
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Biomedical Aspects of Drug Targeting
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Biomedical Aspects of Drug Targeting (Hardcover)
Publicado por
Kluwer Academic Publishers, New York, NY, 2003
ISBN 10: 1402072325
ISBN 13: 9781402072321
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Hardcover. Condición: new. Hardcover. This work includes the general principles of drug targeting, focusing on the cardiovascular system, tumour targeting, brain targeting, miscellaneous targeting and novel approaches for targeting (new horizons). It is designed in a course-like fashion: from more general and simple to more specific and complex material. This framework should help even unfamiliar readers to learn new topics and navigate in the text. Although the book is aimed primarily at industrial and academic pharmacologists and drug discovery researchers, its design will make the book useful for advanced level graduate students. The book focuses on ligand-mediated drug targeting strategies, with additional chapters on general aspects of drug delivery that are of paramount importance in drug targeting (biological barriers, stealth technologies). Included are topics on targeting of genetic materials important in the biomedical context of the ligand-mediated targeting. Drugs usually have no natural affinity for the cells, tissues and organs where therapeutic effects are needed, which frequently results in low efficiency and unwanted side effects. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Nº de ref. del artículo: 9781402072321
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Biomedical Aspects of Drug Targeting
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Gebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Drugs usually have no natural affinity for the cells, tissues and organs where therapeutic effects are needed, which frequently results in low efficiency and unwanted side effects. This concern is even more profound when using highly potent and cytotoxic an. Nº de ref. del artículo: 4094933
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Biomedical Aspects of Drug Targeting
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Condición: New. pp. 532. Nº de ref. del artículo: 262174105
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