A Modular Strategy for Generating Starting Conformations and Data Structures of Polynucleotide Helices for Potential Energy Calculations (Classic Reprint) - Tapa blanda
Sinopsis
Excerpt from A Modular Strategy for Generating Starting Conformations and Data Structures of Polynucleotide Helices for Potential Energy Calculations
Several papers have mentioned in general terms approaches for preparing and linking data structures of single residues to form protein and nucleic acid models [1 Many other papers have described algorithms for generating coordinates for nucleic acid structures when a given set of internal variables bond lengths, bond angles and dihedral angles) is given [4 These algorithms generate structures of dna subunits and then arrange them into helical polymers by using additional helical parameters. The overall strategy is usually that of constrained model building, since a given set of geometric variables is declared independent and other variables are adjusted so as to generate reasonable helical structures. Often, energy minimization is combined to ensure ring closure for the sugars and optimal geometries at the connection sites along the sugar-phosphate backbone.
In some cases, geometry optimization is constrained to maintain, for example, base pairconformations or global helical parameters.
About the Publisher
Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com
This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
"Sinopsis" puede pertenecer a otra edición de este libro.
Otras ediciones populares con el mismo título
Resultados de la búsqueda para A Modular Strategy for Generating Starting Conformations...
Imagen del vendedor
A Modular Strategy for Generating Starting Conformations and Data Structures of
Impresión bajo demandaLibrería: Forgotten Books, London, Reino Unido
Calificación del vendedor: 4 de 5 estrellas
Paperback. Condición: New. Print on Demand. A simple algorithm for generating starting coordinates and data structures of polynucleotide helices for energy calculations is presented in this book. The method is rapid, utilizes a helix from a simple list of bonds for basic DNA subunits, and avoids applying successive transformations to obtain coordinates. Deviations from equilibrium values for P03' bond lengths and 05'-P-O3' bond angles at residue connection sites are permitted, thereby avoiding the need for ring closure and geometry optimization. Every dimer building block is constructed from two sets of variables, one for each strand, and assembled into a helix by rigid body transformations. The author suggests how the algorithm can be used not only to generate standard A, B, and Z-DNA helices, but also to set up a wide range of starting conformations for the purpose of identifying novel helical structures. The book concludes by proposing ways the algorithm can be used to apply the build-up technique and pursue a build-up technique, and to explore conformational space systematically. Its insights will be valuable to those seeking to investigate the base sequence/structure relationship. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item. Nº de ref. del artículo: 9781332869008_0
Comprar nuevo
EUR 15,78
Gastos de envío gratis
Se envía de Reino Unido a Estados Unidos de America
Se envía de Reino Unido a Estados Unidos de America
Cantidad disponible: Más de 20 disponibles
Imagen de archivo
A Modular Strategy for Generating Starting Conformations and Data Structures of Polynucleotide Helices for Potential Energy Calculations (Classic Reprint)
Librería: PBShop.store US, Wood Dale, IL, Estados Unidos de America
Calificación del vendedor: 5 de 5 estrellas
PAP. Condición: New. New Book. Shipped from UK. Established seller since 2000. Nº de ref. del artículo: LW-9781332869008
Comprar nuevo
EUR 22,17
Gastos de envío gratis
Se envía dentro de Estados Unidos de America
Se envía dentro de Estados Unidos de America
Cantidad disponible: 15 disponibles
Imagen de archivo
A Modular Strategy for Generating Starting Conformations and Data Structures of Polynucleotide Helices for Potential Energy Calculations (Classic Reprint)
Librería: PBShop.store UK, Fairford, GLOS, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
PAP. Condición: New. New Book. Shipped from UK. Established seller since 2000. Nº de ref. del artículo: LW-9781332869008
Comprar nuevo
EUR 21,09
Envío por EUR 3,80
Se envía de Reino Unido a Estados Unidos de America
Se envía de Reino Unido a Estados Unidos de America
Cantidad disponible: 15 disponibles