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Sinopsis
Unlock the chemistry behind a famous venom — a detailed, early 20th‑century look at how scientists study Heloderma venom in the lab and what those methods revealed about its chemistry and activity.
This edition presents a focused, method‑driven portrait of biochemical experiments, many described in careful detail.
The book surveys practical lab techniques used to test venom for diastatic activity, peptic digestion, and lipase action, using real experimental setups, solutions, and temperatures. It also discusses observed effects on animals and the challenges of isolating active principles, offering a window into the origins of venom biochemistry and the interpretation of complex results.- Learn the setup of enzyme assays and the kind of data researchers gathered, including temperature controls, reagents, and observed color and precipitate changes.
- See how researchers evaluate the venom’s potential enzymes and its interactions with proteins, fats, and digestive substrates.
- Explore how scientists tested claims about venom components and considered multiple active principles in their analysis.
- Understand the historical context of venom research and how early methods shaped later biochemical study.
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Reseña del editor
Excerpt from The Venom of Heloderma
There exists much difference of Opinion in regard to the real function of the poison gland. Does it merely take up from the blood the poisonous material produced by other cells, or does it actually manufacture the venom from non poisonous substances supplied through blood or lymph? Calmette and Faust accepted the first view. In snakes the blood and, as Flexner and Noguchi found, even the ova contain a venom very similar to that secreted by the poison gland. Calmette and Faust believe, therefore, that the cells of the poison gland have a selective affinity for the venom circulating in the blood. Inas much as Calmette noticed that the heat resistance of the poisonous substance present in the blood differs somewhat from that of the venom secreted by the poison gland, he assumes that a precursor which is poisonous and has been produced by other cells is slightly modified in the poison gland and then secreted. This difference in the heat resistance of the two poisons he regards as a reason sufficient to exclude the view of Phisalix and Bertrand, who regard the venom circulating in the blood as being manufactured in the venom gland and eliminated in the blood through a mechanism related to internal secretion. They found, accordingly, that after extirpation of the venom gland of snakes the blood lost its toxic properties.
In H eloderma conditions are less complicated. Here the venom can not be found anywhere in the body except in the poison gland. Neither does the blood become poisonous after extirpation Of the poison glands, as should be expected if the poison glands served merely as a place of elimination for the venom prepared elsewhere. We can therefore be certain that in the case of H eloderma the poison gland is the place where the venom is produced out of non-poisonous material carried to the gland. Such a conclusion is also in accordance with the view that the granules of the gland are the carriers Of the venom.
About the Publisher
Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com
This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Reseña del editor
Excerpt from The Venom of Heloderma
In H eloderma conditions are less complicated. Here the venom can not be found anywhere in the body except in the poison gland. Neither does the blood become poisonous after extirpation Of the poison glands, as should be expected if the poison glands served merely as a place of elimination for the venom prepared elsewhere. We can therefore be certain that in the case Of H eloderma the poison gland is the place where the venom is produced out of non-poisonous material carried to the gland. Such a conclusion is also in accordance with the view that the granules of the gland are the carriers Of the venom.
About the Publisher
Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com
This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
"Sobre este título" puede pertenecer a otra edición de este libro.
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The Venom of Heloderma (Classic Reprint)
Impresión bajo demandaLibrería: Forgotten Books, London, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
Paperback. Condición: New. Print on Demand. This book thoroughly examines the properties and toxic effects of the venom of Heloderma, a species of venomous lizard. The author undertook this study at the request of Dr. S. Weir Mitchell and carried out the research using grants from the Carnegie Institution of Washington. To extend the research in various directions, the author collaborated with other scientists who studied various aspects of the problem. The book is a collection of their findings. The author reviews the literature on the subject, discusses methods of collecting the venom, and factors that influence the amount of secretion. It also delves into the effects of heat, standing in solution, dialysis, filtration, addition of acid to venom solution, Roentgen rays on secretion of venom gland, and venom upon animals. Furthermore, the book details the author's original histological, bacteriological, biochemical, and experimental studies on the venom, which provide new insights into its nature and effects. The book concludes with a discussion of the significance of the findings, which contribute to our understanding of the venom of Heloderma and its potential medical applications. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item. Nº de ref. del artículo: 9781332801374_0
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The Venom of Heloderma Classic Reprint
Librería: PBShop.store US, Wood Dale, IL, Estados Unidos de America
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PAP. Condición: New. New Book. Shipped from UK. Established seller since 2000. Nº de ref. del artículo: LW-9781332801374
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The Venom of Heloderma Classic Reprint
Librería: PBShop.store UK, Fairford, GLOS, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
PAP. Condición: New. New Book. Shipped from UK. Established seller since 2000. Nº de ref. del artículo: LW-9781332801374
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