Models of Life: Dynamics and Regulation in Biological Systems

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9781107061903: Models of Life: Dynamics and Regulation in Biological Systems

Focusing on simple models, this book describes methods for studying the quantitative aspects of life through physical modelling, using E. coli and phage lambda as key examples. It encompasses fields such as quantitative molecular biology, systems biology and biophysics, providing a tool for students from both biological and physical science backgrounds.

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'Models of Life is an insight of a physicist into biological regulatory mechanisms. It provides quantitative basis of how many of the biological systems work. Using simple logic and mathematics, Kim Sneppen, a world renowned scientist and thinker, has created a 'must' reading for investigators in quantitative biology. The book provides a clear explanation of triumphant experiments in a lucid way with crisp figures. The brilliance of the author's analytical mind is on display when one sees how he explains beginning with the basics of molecular biology some of the exciting paradigmatic regulatory systems. The book is also replete with intellectually challenging problem questions for readers making the book even an excellent text for students as well.' Sankar Adhya, National Cancer Institute, Maryland

'Kim Sneppen's insightful book covers lots of ground in describing biological systems at different time and length scales and levels of resolution. Its different chapters unified by author's modeling philosophy are sure to be of interest to a very diverse group of readers. … Readers interested in agent-based modeling will find it applies to systems as diverse as epigenetics, propagation of information, and evolutionary patterns in fossil record. Dedicated chapters combine biophysics and systems biology of gene regulation and protein-protein interactions. The book provides especially deep coverage of biology of phages, bacteria and their interactions within ecosystems. It would make an excellent textbook for one or even several university courses on systems or evolutionary biology. In fact when teaching these courses I will use it heavily myself and recommend it to my students.' Sergei Maslov, Brookhaven National Laboratory

'Sneppen has written a wonderfully friendly and readable book on the principles of biological cells for physicists. He presents concepts and models at a level that is sufficiently deep to convey powerful insights, while keeping the math to the absolutely minimal level that is needed to be clear and informative. This book is pioneering in covering scientific terrain that is largely not covered much elsewhere, but will be in the future - including feedback, regulation, networks, bistability in the lambda-phage switch, DNA looping, diffusion in cells, epigenetic regulation and cellular evolution. I highly recommend it as a deeply insightful book about the principles of biology and a great read.' Ken Dill, Laufer Center, Stony Brook University

Reseña del editor:

Reflecting the major advances that have been made in the field over the past decade, this book provides an overview of current models of biological systems. The focus is on simple quantitative models, highlighting their role in enhancing our understanding of the strategies of gene regulation and dynamics of information transfer along signalling pathways, as well as in unravelling the interplay between function and evolution. The chapters are self-contained, each describing key methods for studying the quantitative aspects of life through the use of physical models. They focus, in particular, on connecting the dynamics of proteins and DNA with strategic decisions on the larger scale of a living cell, using E. coli and phage lambda as key examples. Encompassing fields such as quantitative molecular biology, systems biology and biophysics, this book will be a valuable tool for students from both biological and physical science backgrounds.

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Kim Sneppen
Editorial: CAMBRIDGE UNIVERSITY PRESS, United Kingdom (2014)
ISBN 10: 1107061903 ISBN 13: 9781107061903
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Descripción CAMBRIDGE UNIVERSITY PRESS, United Kingdom, 2014. Hardback. Estado de conservación: New. 246 x 180 mm. Language: English . Brand New Book. Reflecting the major advances that have been made in the field over the past decade, this book provides an overview of current models of biological systems. The focus is on simple quantitative models, highlighting their role in enhancing our understanding of the strategies of gene regulation and dynamics of information transfer along signalling pathways, as well as in unravelling the interplay between function and evolution. The chapters are self-contained, each describing key methods for studying the quantitative aspects of life through the use of physical models. They focus, in particular, on connecting the dynamics of proteins and DNA with strategic decisions on the larger scale of a living cell, using E. coli and phage lambda as key examples. Encompassing fields such as quantitative molecular biology, systems biology and biophysics, this book will be a valuable tool for students from both biological and physical science backgrounds. Nº de ref. de la librería AAA9781107061903

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Kim Sneppen
Editorial: Cambridge University Press 2014-10-02, Cambridge (2014)
ISBN 10: 1107061903 ISBN 13: 9781107061903
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Descripción Cambridge University Press 2014-10-02, Cambridge, 2014. hardback. Estado de conservación: New. Nº de ref. de la librería 9781107061903

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Kim Sneppen
Editorial: CAMBRIDGE UNIVERSITY PRESS, United Kingdom (2014)
ISBN 10: 1107061903 ISBN 13: 9781107061903
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Descripción CAMBRIDGE UNIVERSITY PRESS, United Kingdom, 2014. Hardback. Estado de conservación: New. 246 x 180 mm. Language: English . Brand New Book. Reflecting the major advances that have been made in the field over the past decade, this book provides an overview of current models of biological systems. The focus is on simple quantitative models, highlighting their role in enhancing our understanding of the strategies of gene regulation and dynamics of information transfer along signalling pathways, as well as in unravelling the interplay between function and evolution. The chapters are self-contained, each describing key methods for studying the quantitative aspects of life through the use of physical models. They focus, in particular, on connecting the dynamics of proteins and DNA with strategic decisions on the larger scale of a living cell, using E. coli and phage lambda as key examples. Encompassing fields such as quantitative molecular biology, systems biology and biophysics, this book will be a valuable tool for students from both biological and physical science backgrounds. Nº de ref. de la librería AAA9781107061903

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Sneppen, Kim
Editorial: Cambridge University Press (2014)
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Descripción Cambridge University Press, 2014. HRD. Estado de conservación: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Nº de ref. de la librería FM-9781107061903

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Sneppen, Kim
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ISBN 10: 1107061903 ISBN 13: 9781107061903
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Descripción Cambridge Univ Pr, 2014. HRD. Estado de conservación: New. New Book. Shipped from US within 10 to 14 business days. Established seller since 2000. Nº de ref. de la librería VM-9781107061903

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Sneppen, Kim
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Descripción Cambridge Univ Pr, 2014. HRD. Estado de conservación: New. New Book.Shipped from US within 10 to 14 business days. Established seller since 2000. Nº de ref. de la librería IB-9781107061903

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Sneppen, Kim
Editorial: Cambridge Univ Pr (2014)
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Descripción Cambridge Univ Pr, 2014. Hardcover. Estado de conservación: Brand New. 342 pages. 9.75x7.00x1.00 inches. In Stock. Nº de ref. de la librería __1107061903

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KIM SNEPPEN
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Descripción 2014. Hardback. Estado de conservación: NEW. 9781107061903 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Nº de ref. de la librería HTANDREE0743436

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Kim Sneppen
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Descripción CAMBRIDGE UNIVERSITY PRESS, United Kingdom, 2014. Hardback. Estado de conservación: New. 246 x 180 mm. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. Reflecting the major advances that have been made in the field over the past decade, this book provides an overview of current models of biological systems. The focus is on simple quantitative models, highlighting their role in enhancing our understanding of the strategies of gene regulation and dynamics of information transfer along signalling pathways, as well as in unravelling the interplay between function and evolution. The chapters are self-contained, each describing key methods for studying the quantitative aspects of life through the use of physical models. They focus, in particular, on connecting the dynamics of proteins and DNA with strategic decisions on the larger scale of a living cell, using E. coli and phage lambda as key examples. Encompassing fields such as quantitative molecular biology, systems biology and biophysics, this book will be a valuable tool for students from both biological and physical science backgrounds. Nº de ref. de la librería BTE9781107061903

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Descripción Cambridge University Press, 2014. Hardcover. Estado de conservación: New. Nº de ref. de la librería 1107061903

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