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Chromatin Accessibility: Methods and Protocols: 2611 (Methods in Molecular Biology, 2611) - Tapa dura

Libro 237 de 381: Methods in Molecular Biology
 
9781071628980: Chromatin Accessibility: Methods and Protocols: 2611 (Methods in Molecular Biology, 2611)
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ISBN 10: 1071628984 ISBN 13: 9781071628980
Editorial: Humana, 2023

Sinopsis

This detailed volume provides a comprehensive resource covering the existing and state-of-the-art tools in the field of profiling chromatin accessibility and its dynamics. Beginning with a section on bulk-cell methods for profiling chromatin accessibility and nucleosome positioning that rely on enzymatic cleavage of accessible DNA and produce information about relative accessibility, the book continues with methods that use single-molecule and enzymatic approaches to solving the problem of mapping absolute occupancy/accessibility, emerging tools for mapping DNA accessibility and nucleosome positioning in single cells, imaging-based methods for visualizing accessible chromatin in its nuclear context, as well as computational methods for the processing and analysis of chromatin accessibility datasets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 


Authoritative and up-to-date, Chromatin Accessibility: Methods and Protocols serves as an extensive and useful reference for researchers studying different facets of chromatin accessibility in a wide variety of biological contexts. 

Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

"Sinopsis" puede pertenecer a otra edición de este libro.

De la contraportada

This detailed volume provides a comprehensive resource covering the existing and state-of-the-art tools in the field of profiling chromatin accessibility and its dynamics. Beginning with a section on bulk-cell methods for profiling chromatin accessibility and nucleosome positioning that rely on enzymatic cleavage of accessible DNA and produce information about relative accessibility, the book continues with methods that use single-molecule and enzymatic approaches to solving the problem of mapping absolute occupancy/accessibility, emerging tools for mapping DNA accessibility and nucleosome positioning in single cells, imaging-based methods for visualizing accessible chromatin in its nuclear context, as well as computational methods for the processing and analysis of chromatin accessibility datasets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and up-to-date, Chromatin Accessibility: Methods and Protocols serves as an extensive and useful reference for researchers studying different facets of chromatin accessibility in a wide variety of biological contexts.
Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Humana
Año de publicación
2023
Idioma
Inglés
ISBN 10 
1071628984
ISBN 13 
9781071628980
Encuadernación
Tapa dura
Número de edición
1
Número de páginas
356
Editor
Marinov Georgi K., Greenleaf William J.
Contacto del fabricante
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