Statistics in Toxicology Using R (Chapman & Hall/CRC The R Series) - Tapa blanda

Libro 20 de 73: Chapman & Hall/CRC The R

Hothorn, Ludwig A.

 
9781032098135: Statistics in Toxicology Using R (Chapman & Hall/CRC The R Series)
Tapa blanda
ISBN 10: 1032098139 ISBN 13: 9781032098135
Editorial: Routledge, 2021

Sinopsis

The apparent contradiction between statistical significance and biological relevance has diminished the value of statistical methods as a whole in toxicology. Moreover, recommendations for statistical analysis are imprecise in most toxicological guidelines. Addressing these dilemmas, Statistics in Toxicology Using R explains the statistical analysis of selected experimental data in toxicology and presents assay-specific suggestions, such as for the in vitro micronucleus assay.

Mostly focusing on hypothesis testing, the book covers standardized bioassays for chemicals, drugs, and environmental pollutants. It is organized according to selected toxicological assays, including:



  • Short-term repeated toxicity studies


  • Long-term carcinogenicity assays


  • Studies on reproductive toxicity


  • Mutagenicity assays


  • Toxicokinetic studies

The book also discusses proof of safety (particularly in ecotoxicological assays), toxicogenomics, the analysis of interlaboratory studies and the modeling of dose-response relationships for risk assessment. For each toxicological problem, the author describes the statistics involved, matching data example, R code, and outcomes and their interpretation. This approach allows you to select a certain bioassay, identify the specific data structure, run the R code with the data example, understand the test outcome and interpretation, and replace the data set with your own data and run again.

"Sinopsis" puede pertenecer a otra edición de este libro.

Acerca del autor

Ludwig A. Hothorn is a professor in the Institute of Biostatistics at the Leibniz University of Hannover. Dr. Hothorn has published more than 130 papers in peer-reviewed journals and contributed numerous book chapters. His research interests include computational statistics using R as well as the application of statistical methods in biology, agriculture, medicine, life sciences, toxicology, pharmacology, and quantitative genetics.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Routledge
Año de publicación
2021
Idioma
Inglés
ISBN 10 
1032098139
ISBN 13 
9781032098135
Encuadernación
Tapa blanda
Número de edición
1
Número de páginas
252
Contacto del fabricante
no disponible
Persona responsable
gpsr@libri.de
gpsr@libri.de

Friedensallee 273
Hamburg
22763
Alemania

Otras ediciones populares con el mismo título

9781498701273: Statistics in Toxicology Using R (Chapman & Hall/CRC The R Series)

Edición Destacada

ISBN 10:  1498701272 ISBN 13:  9781498701273
Editorial: Chapman and Hall/CRC, 2015
Tapa dura