Genome-Scale Algorithm Design: Bioinformatics in the Era of High-Throughput Sequencing - Tapa dura

Mäkinen, Veli; Belazzougui, Djamal; Cunial, Fabio; Tomescu, Alexandru I.

 
9781009341233: Genome-Scale Algorithm Design: Bioinformatics in the Era of High-Throughput Sequencing
Tapa dura
ISBN 10: 1009341235 ISBN 13: 9781009341233
Editorial: Cambridge University Press, 2023

Sinopsis

Presenting the fundamental algorithms and data structures that power bioinformatics workflows, this book covers a range of topics from the foundations of sequence analysis (alignments and hidden Markov models) to classical index structures (k-mer indexes, suffix arrays, and suffix trees), Burrows–Wheeler indexes, graph algorithms, network flows, and a number of advanced omics applications. The chapters feature numerous examples, algorithm visualizations, and exercises, providing graduate students, researchers, and practitioners with a powerful algorithmic toolkit for the applications of high-throughput sequencing. An accompanying website (www.genome-scale.info) offers supporting teaching material. The second edition strengthens the toolkit by covering minimizers and other advanced data structures and their use in emerging pangenomics approaches.

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Acerca del autor

Veli Mäkinen is Professor of Computer Science at the University of Helsinki, where he leads a research team on genome-scale algorithmics. He has taught advanced courses on algorithm design and analysis, string processing, data compression, and algorithmic genome analysis, as well as introductory courses on bioinformatics. Djamal Belazzougui is a permanent researcher at the Research Centre for Scientific and Technical Information in Algiers, Algeria. He worked in the Genome-Scale Algorithmics group at the University of Helsinki as a postdoctoral researcher from 2012 to 2015. His research topics include hashing, succinct and compressed data structures, string algorithms, and bioinformatics. Fabio Cunial is a computational scientist at the Broad Institute of MIT and Harvard. He has served as a postdoctoral researcher at the Genome-Scale Algorithmics group at the University of Helsinki as well as at the Myers lab in Dresden. Alexandru I. Tomescu is Associate Professor of Algorithmic Bioinformatics at the University of Helsinki, where he leads a research group on graph algorithms and their application to high-throughput sequencing problems. He is the recipient of a Starting Grant from the European Research Council.

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Editorial
Cambridge University Press
Año de publicación
2023
Idioma
Inglés
ISBN 10 
1009341235
ISBN 13 
9781009341233
Encuadernación
Tapa dura
Número de edición
2
Número de páginas
470
Contacto del fabricante
no disponible
Persona responsable
Avery
https://www.avery.fr/

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