This textbook shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data.
The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure.
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Brian and Deborah Charlesworth obtained PhDs in genetics at the University of Cambridge, and have subsequently worked at the Universities of Liverpool, Sussex, Chicago, and Edinburgh. They are the authors of Evolution: A Very Short Introduction, a book for the general public. Brian is a Fellow of the Royal Society and Honorary Fellow of the American Academy of Arts and Sciences, and Deborah is a Fellow of the Royal Society. Both currently work on questions in population genetics, molecular and genome evolution, and also on mating system evolution.
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