Of Urfs and Orfs: A primer on how to analyze derived amino acid sequences - Tapa blanda

Doolittle, Russell F.

9780935702545: Of Urfs and Orfs: A primer on how to analyze derived amino acid sequences

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ISBN 10: 0935702547 ISBN 13: 9780935702545

Editorial: University Science Books,U.S., 1987

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In these days of facile cloning and rapid DNA sequencing, it is not uncommon for investigators to find themselves with a DNA sequence that may or may not code for a known gene product. The sequence is 'open' when read in an appropriate frame, which is to say that there is a long run of amino acid codons before the appearance of a terminator codon. How can we find out if this 'unidentified reading frame' (URF) really codes for a genuine protein, and how can we identify it if it exists? There are two general strategies, both of which can also be applied to the characterization of any 'open reading frame' (ORF), whether or not it has been 'identified'. The first and simplest approach involves computer searching and analysis; the second employs antibodies raised against synthetic peptides patterned on the sequence of the expected gene product. Both methods have been used with great success by many investigators. Each has, nonetheless, its pitfalls and frustrations. This primer is meant to guide the researcher past those obstacles as much as possible. Graduate students and researchers interested in amino acid sequencing; molecular biologists, biochemists, chemists, and biotechnologists.

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Russell F. Doolittle is an emeritus professor at the University of California, San Diego, where he has spent most of his long career. Her received his PhD in biochemistry from Harvard University in 1962. His research interests have centered on the structure and evolution of proteins in general and, more particularly, on blood clotting proteins, an interest he developed while a graduate student at Harvard. He is a member of the US National Academy of Sciences, the American Academy of Arts and Sciences, and the American Philosophical Society.

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EditorialUniversity Science Books,U.S.
A�o de publicaci�n1987
ISBN 10 0935702547
ISBN 13 9780935702545
Encuadernaci�nTapa blanda
IdiomaIngl�s
N�mero de p�ginas103
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Of Urfs And Orfs: A Primer on How to Analyze Derived Amino Acid Sequences

Doolittle, Russell F

Publicado por University Science Books, 1991

ISBN 10: 0935702547 ISBN 13: 9780935702545

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Of URFS and ORFS: A Primer on How to Analyze Derived Amino Acid Sequences

Doolittle, R.F.

Publicado por University Science Books, 1986

ISBN 10: 0935702547 ISBN 13: 9780935702545

Antiguo o usado Tapa blanda

Librería: Anybook.com, Lincoln, Reino Unido

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Condici�n: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Clean from markings. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,350grams, ISBN:0935702547. N� de ref. del art�culo: 8655941

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Of Urfs and Orfs: A Primer on How to Analyze Derived Amino Acid Sequences

Doolittle, Russell F.

Publicado por University Science Books, 1986

ISBN 10: 0935702547 ISBN 13: 9780935702545

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Of Urfs and Orfs: A Primer on How to Analyze Derived Amino Acid Sequences

Russell F. Doolittle

Publicado por University Science Books,U.S., 1991

ISBN 10: 0935702547 ISBN 13: 9780935702545

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Softcover. Condici�n: Bon. L�g�res traces d'usure sur la couverture. Edition 1991. Ammareal reverse jusqu'� 15% du prix net de cet article � des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Good. Slight signs of wear on the cover. Edition 1991. Ammareal gives back up to 15% of this item's net price to charity organizations. N� de ref. del art�culo: C-827-179

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Of Urfs and Orfs: A Primer on How to Analyze Derived Amino Acid Sequences

Doolittle, R. F

Publicado por University Science Books, 1987

ISBN 10: 0935702547 ISBN 13: 9780935702545

Antiguo o usado Tapa blanda

Librería: Anybook.com, Lincoln, Reino Unido

Calificaci�n del vendedor: 5 de 5 estrellas

Condici�n: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Clean from markings. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,400grams, ISBN:0935702547. N� de ref. del art�culo: 9147207

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Of Urfs and Orfs: A Primer on How to Analyze Derived Amino Acid Sequences

Doolittle, R. F.

Publicado por University Science Books, 1986

ISBN 10: 0935702547 ISBN 13: 9780935702545

Antiguo o usado Tapa blanda

Librería: Anybook.com, Lincoln, Reino Unido

Calificaci�n del vendedor: 5 de 5 estrellas

Condici�n: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. In fair condition, suitable as a study copy. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,300grams, ISBN:0935702547. N� de ref. del art�culo: 9507493

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