Colorectal Cancer: Methods and Protocols: 50 (Methods in Molecular Medicine, 50) - Tapa dura

 
9780896037670: Colorectal Cancer: Methods and Protocols: 50 (Methods in Molecular Medicine, 50)
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ISBN 10: 0896037673 ISBN 13: 9780896037670
Editorial: Humana Press, 2000

Sinopsis

The contents of Colorectal Cancer: Methods and Protocols aim to instruct investigators in all the key genetic, cellular, and molecular biological methods of analyzing colorectal tumors. The focused techniques and assays are described in sufficient detail to allow researchers to start an experiment on colon tumors and proceed from beginning to end as if the expert in the field who has performed these studies were guiding them at the bench. Of note, most of the chapters in this volume are written by those scientists who p- neered these methods and assays in their respective fields. The chapters in Colorectal Cancer: Methods and Protocols describe "state of the art" methods to analyze colorectal tumors, ranging from gross mic- dissection of specimens to specific molecular analyses. Included are coverages of mutational assays, instability testing, immunohistochemical assays, chro- somal studies, and gene expression analyses. The goal of our volume is to facilitate the performance of colorectal tumor biological experiments by investigators at various levels of training-from graduate students and postdoctoral fellows to principal investigators who desire to advance our understanding of colon cancer development.

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De la contraportada

Colorectal cancer is a common and highly lethal cancer once spread whose treatment is improving as we gain a better understanding of its development. In Colorectal Cancer: Methods and Protocols, Steven M. Powell, MD, has assembled a hands-on collection of cutting-edge molecular methods for studying this solid tumor. These readily reproducible techniques range from gross microdissection of specimens to specific molecular analyses. Here both the novice and experienced researcher will find productive chromosomal analyses, including comparative genomic hybridization and FISH assays, and revealing gene expression analyses, including immunohistochemical assays, Western blotting, and microarray assays. Also presented are mutational analyses of colon tumors and blood samples to determine whether specific patients have inherited a significant predisposition to colorectal cancer. Each method is described in step-by-step detail by an established expert to ensure robust experimental results, and all are accompanied by detailed notes on pitfalls to avoid.
Eminently practical, with each technique presented as if the expert in the field who had perfected it were guiding the investigator, Colorectal Cancer: Methods and Protocols provides cancer investigators with a gold standard collection of all the key genetic, cellular, and molecular biological methods for analyzing colon cancer today.

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Editorial
Humana Press
Año de publicación
2000
Idioma
Inglés
ISBN 10 
0896037673
ISBN 13 
9780896037670
Encuadernación
Tapa dura
Número de páginas
312
Editor
Powell Steven M.
Contacto del fabricante
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Alemania

Otras ediciones populares con el mismo título

9781617371790: Colorectal Cancer: Methods and Protocols: 50 (Methods in Molecular Medicine)

Edición Destacada

ISBN 10:  1617371793 ISBN 13:  9781617371790
Editorial: Humana, 2010
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