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Matrix Metalloproteinase Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development) - Tapa dura

Libro 7 de 96: Cancer Drug Discovery and Development
 
9780896036680: Matrix Metalloproteinase Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development)
Tapa dura
ISBN 10: 0896036685 ISBN 13: 9780896036680
Editorial: Springer, 2000

Sinopsis

Cutting-edge investigators review the current status of the entire field, from the biology of MMPs through the current clinical studies. The authors include many leading scientists from pharmaceutical companies who present all the latest concepts and results on the preferred design strategies for MMP inhibitors, their molecular mechanisms, and their substrates. In addition, they fully describe their personal research on specific MMP inhibitors, detailing vanguard design strategies, their in vitro activity, the outcome of animal model studies and, where available, their toxicology, safety, efficacy in human clinical trials.
Comprehensive and state-of-the-art, Matrix Metalloproteinase Inhibitors in Cancer Therapy offers basic and clinical investigators alike a richly informative summary of all the latest research on these powerful new drugs, and their high promise as emerging cancer therapeutics.

"Sinopsis" puede pertenecer a otra edición de este libro.

De la contraportada

The association of matrix metalloproteinases (MMPs)-enzymes that disrupt the body's normal repair functions-with several diseases, including growing and invasive tumors, holds the tantalizing promise that their inhibiton might have therapeutic value. In Matrix Metalloproteinase Inhibitors in Cancer Therapy, cutting-edge investigators review the current status of the entire field, from the biology of MMPs through the current clinical studies. The authors include many leading scientists from pharmaceutical companies who present all the latest concepts and results on the preferred design strategies for MMP inhibitors, their molecular mechanisms, and their substrates. In addition, they fully describe their company's research effort on specific MMP inhibitors, detailing vanguard design strategies, their in vitro activity, the outcome of animal model studies and, where available, their toxicology, safety, and efficacy in human clinical trials. Comprehensive and state-of-the-art, Matrix Metalloproteinase Inhibitors offers basic and clinical investigators alike a richly informative summary of all the latest research on these powerful new drugs, and their high promise as emerging cancer therapeutics.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Springer
Año de publicación
2000
Idioma
Inglés
ISBN 10 
0896036685
ISBN 13 
9780896036680
Encuadernación
Tapa dura
Número de páginas
262
Editor
Clendeninn Neil J., Appelt Krzysztof
Contacto del fabricante
no disponible
Persona responsable
no disponible