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Sinopsis
A team of expert investigators and clinical researchers comprehensively review complement's basic biology, its role in disease, methods to measure its activity, and strategies for its inhibition in patients. Each chapter focuses on a specific area of basic and applied complement biology, spelling out the activation pathways and complement receptors. Informative animal models are discussed in detail, including the relative values of each model and the important interspecies differences that can distort the interpretation of preclinical studies. The emphasis throughout is on the pros and cons of the therapeutic use of recombinant complement inhibitors in specific diseases. Cutting-edge and innovative, Therapeutic Interventions in the Complement System highlights for today's researcher and biotechnologist effective strategies of drug discovery and development that are producing valuable new complement inhibitors for the treatment of a wide variety of clinically important diseases.
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De la contraportada
Although the complement system is a vital part of the body's defenses against bacteria, its inappropriate activation produces the cell damage found in a wide variety of illnesses, ranging from hemolytic anemia to multiple sclerosis. In Therapeutic Interventions in the Complement System, a team of expert investigators and researchers comprehensively review complement's basic biology, its role in disease, methods to measure its activity, and strategies for its inhibition in patients. Each chapter focuses on a specific area of basic and applied complement biology, detailing the activation pathways and complement receptors. Informative animal models are thoroughly discussed, including the relative values of each model and the important interspecies differences that can distort the interpretation of preclinical studies. Also discussed are analytical issues concerning the sensitivity and specificity of the important new ELISA assays for measuring complement. Throughout, the emphasis is on the pros and cons of the use of recombinant complement inhibitors as therapeutics in specific diseases.
Cutting-edge and innovative, Therapeutic Interventions in the Complement System highlights for clinical researchers and biotechnologists the powerful drug discovery and development strategies that are producing the novel complement inhibitors today emerging for the treatment of a wide variety of clinically important diseases.
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Therapeutic Interventions in the Complement System (Contemporary Immunology)
Librería: BOOKWEST, Phoenix, AZ, Estados Unidos de America
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Therapeutic Interventions in the Complement System
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Humana Press, Totowa, N.J., 2000
ISBN 10: 0896035875
ISBN 13: 9780896035874
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Librería: BIBLIOPE by Calvello Books, Oakland, CA, Estados Unidos de America
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Hardcover. Condición: Near fine. Octavo in red and white illus. boards; 259 p.: ill.; Includes bibliographical references and index. Series: Contemporary immunology; Complement System Proteins -- immunology. Complement Activation -- physiology. Complement Inactivator Proteins -- physiology. Near fine++ to fine(-) with very minor rubbed corners ; else tight and clean. No markings within. Nº de ref. del artículo: 82736
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Therapeutic Interventions in the Complement System [Contemporary Immunology 9]
Publicado por
Humana Press, Totowa, N.J., 2000
ISBN 10: 0896035875
ISBN 13: 9780896035874
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Librería: Tiber Books, Cockeysville, MD, Estados Unidos de America
Calificación del vendedor: 4 de 5 estrellas
Hardcover. Condición: New. 8vo, hardcover. NEW. Bright, crisp & clean, unread. ix, 259 p., illus. Nº de ref. del artículo: 1030116.29
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Therapeutic Interventions in the Complement System
Librería: Majestic Books, Hounslow, Reino Unido
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Condición: New. pp. 272 9:B&W 6 x 9 in or 229 x 152 mm Case Laminate on Creme w/Gloss Lam. Nº de ref. del artículo: 7590588
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Therapeutic Interventions in the Complement System
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Condición: New. pp. 272. Nº de ref. del artículo: 26290147
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Therapeutic Interventions in the Complement System
Librería: Biblios, Frankfurt am main, HESSE, Alemania
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Condición: New. pp. 272. Nº de ref. del artículo: 18290153
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Therapeutic Interventions In The Complement System
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Therapeutic Interventions in the Complement System (Contemporary Immunology)
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Therapeutic Interventions in the Complement System (Contemporary Immunology)
Librería: ALLBOOKS1, Direk, SA, Australia
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Therapeutic Interventions in the Complement System
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