Immunoreceptor Signaling (Cold Spring Harbor Perspectives in Biology)

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9780879698966: Immunoreceptor Signaling (Cold Spring Harbor Perspectives in Biology)
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The behavior of lymphocytes in the immune system depends on encounters with antigens. These bind to immunoreceptors on the surface of T-cells and B-cells, activating a variety of signal transduction pathways that control cell survival, proliferation, differentiation, and effector functions.
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology includes contributions covering the structures of the T-cell and B-cell immunoreceptors, the numerous kinases and adaptors that associate with their intracellular tails, and the downstream signaling pathways that lead to transcription of interleukins and other outputs. Other contributions examine the roles of other receptors, co-stimulatory signals, and innate immune responses in regulation of immunoreceptor signaling. The spatial organization of the immunological synapses connecting lymphocytes and antigen-presenting cells is also discussed, along with the role of the cytoskeleton in immunoreceptor function. Computational models of the signaling processes complete the volume, making it essential reading for systems biologists as well as all immunologists and cell biologists interested in understanding how lymphocytes function.

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Editorial: Cold Spring Harbor Laboratory Press,U.S., United States (2010)
ISBN 10: 0879698969 ISBN 13: 9780879698966
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Descripción Cold Spring Harbor Laboratory Press,U.S., United States, 2010. Hardback. Estado de conservación: New. 259 x 183 mm. Language: English . Brand New Book. The behavior of lymphocytes in the immune system depends on encounters with antigens. These bind to immunoreceptors on the surface of T-cells and B-cells, activating a variety of signal transduction pathways that control cell survival, proliferation, differentiation, and effector functions. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology includes contributions covering the structures of the T-cell and B-cell immunoreceptors, the numerous kinases and adaptors that associate with their intracellular tails, and the downstream signaling pathways that lead to transcription of interleukins and other outputs. Other contributions examine the roles of other receptors, co-stimulatory signals, and innate immune responses in regulation of immunoreceptor signaling. The spatial organization of the immunological synapses connecting lymphocytes and antigen-presenting cells is also discussed, along with the role of the cytoskeleton in immunoreceptor function. Computational models of the signaling processes complete the volume, making it essential reading for systems biologists as well as all immunologists and cell biologists interested in understanding how lymphocytes function. Nº de ref. de la librería AAR9780879698966

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Lawrence E. Samelson, Andrey Shaw
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Descripción Oxford University Press. Estado de conservación: New. Brand New. Nº de ref. de la librería 0879698969

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Editorial: Cold Spring Harbor Laboratory Press,U.S., United States (2010)
ISBN 10: 0879698969 ISBN 13: 9780879698966
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Descripción Cold Spring Harbor Laboratory Press,U.S., United States, 2010. Hardback. Estado de conservación: New. 259 x 183 mm. Language: English . Brand New Book. The behavior of lymphocytes in the immune system depends on encounters with antigens. These bind to immunoreceptors on the surface of T-cells and B-cells, activating a variety of signal transduction pathways that control cell survival, proliferation, differentiation, and effector functions. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology includes contributions covering the structures of the T-cell and B-cell immunoreceptors, the numerous kinases and adaptors that associate with their intracellular tails, and the downstream signaling pathways that lead to transcription of interleukins and other outputs. Other contributions examine the roles of other receptors, co-stimulatory signals, and innate immune responses in regulation of immunoreceptor signaling. The spatial organization of the immunological synapses connecting lymphocytes and antigen-presenting cells is also discussed, along with the role of the cytoskeleton in immunoreceptor function. Computational models of the signaling processes complete the volume, making it essential reading for systems biologists as well as all immunologists and cell biologists interested in understanding how lymphocytes function. Nº de ref. de la librería AAR9780879698966

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Lawrence E Samelson, Andrey Shaw
Editorial: Cold Spring Harbor Laboratory Press,U.S.
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Descripción Cold Spring Harbor Laboratory Press,U.S. Hardback. Estado de conservación: new. BRAND NEW, Immunoreceptor Signaling, Lawrence E Samelson, Andrey Shaw, The behavior of lymphocytes in the immune system depends on encounters with antigens. These bind to immunoreceptors on the surface of T-cells and B-cells, activating a variety of signal transduction pathways that control cell survival, proliferation, differentiation, and effector functions. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology includes contributions covering the structures of the T-cell and B-cell immunoreceptors, the numerous kinases and adaptors that associate with their intracellular tails, and the downstream signaling pathways that lead to transcription of interleukins and other outputs. Other contributions examine the roles of other receptors, co-stimulatory signals, and innate immune responses in regulation of immunoreceptor signaling. The spatial organization of the immunological synapses connecting lymphocytes and antigen-presenting cells is also discussed, along with the role of the cytoskeleton in immunoreceptor function. Computational models of the signaling processes complete the volume, making it essential reading for systems biologists as well as all immunologists and cell biologists interested in understanding how lymphocytes function. Nº de ref. de la librería B9780879698966

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Lawrence E Samelson
Editorial: Cold Spring Harbor Laboratory Press,U.S. (2010)
ISBN 10: 0879698969 ISBN 13: 9780879698966
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Descripción Cold Spring Harbor Laboratory Press,U.S., 2010. HRD. Estado de conservación: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Nº de ref. de la librería CW-9780879698966

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ISBN 10: 0879698969 ISBN 13: 9780879698966
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Descripción Estado de conservación: New. Depending on your location, this item may ship from the US or UK. Nº de ref. de la librería 97808796989660000000

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Samelson, Lawrence E./ Shaw, Andrey
Editorial: Cold Spring Harbor Laboratory Pr (2010)
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Descripción Cold Spring Harbor Laboratory Pr, 2010. Hardcover. Estado de conservación: Brand New. 1st edition. 282 pages. 10.25x7.25x0.75 inches. In Stock. Nº de ref. de la librería __0879698969

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Editorial: Cold Spring Harbor Laboratory Press (2010)
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Descripción Cold Spring Harbor Laboratory Press, 2010. Hardcover. Estado de conservación: New. book. Nº de ref. de la librería 0879698969

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