Generation and Interpretation of Morphogen Gradients (Cold Spring Harbor Laboratory) - Tapa dura

 
9780879698812: Generation and Interpretation of Morphogen Gradients (Cold Spring Harbor Laboratory)
Tapa dura
ISBN 10: 0879698810 ISBN 13: 9780879698812
Editorial: Cold Spring Harbor Laboratory Press,U.S., 2010

Sinopsis

Signaling by diffusible morphogens, such as Hedgehog, Wingless, TGF-ß, and various growth factors, is essential during embryogenesis. The establishment of concentration gradients of these morphogens is vital for developmental patterning, ensuring that distinct differentiated cell types appear in the right place and at the right time in forming tissues.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology explores how morphogen gradients are generated and interpreted during development. The contributors examine the regulation of morphogen synthesis, trafficking, and diffusion, as well as the complex webs of signaling mechanisms and transcriptional responses in recipient cells --whose fates are dictated by these morphogens. Including discussion of the roles of morphogen gradients in various tissues in organisms from yeast to humans, the volume is a vital reference for developmental biologists and cell biologists wishing to know how cell fate is determined during embryogenesis.

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Reseña del editor

Signaling by diffusible morphogens, such as Hedgehog, Wingless, TGF-ß, and various growth factors, is essential during embryogenesis. The establishment of concentration gradients of these morphogens is vital for developmental patterning, ensuring that distinct differentiated cell types appear in the right place and at the right time in forming tissues.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology explores how morphogen gradients are generated and interpreted during development. The contributors examine the regulation of morphogen synthesis, trafficking, and diffusion, as well as the complex webs of signaling mechanisms and transcriptional responses in recipient cells --whose fates are dictated by these morphogens. Including discussion of the roles of morphogen gradients in various tissues in organisms from yeast to humans, the volume is a vital reference for developmental biologists and cell biologists wishing to know how cell fate is determined during embryogenesis.

Reseña del editor

Signalling by morphogens such as the Hedgehog family, Notch, Wingless/Wnt and various growth factors is essential during embryogenesis. The establishment of concentration gradients of these morphogens plays a key role during developmental patterning in all multicellular organisms, assuring that distinct cell/tissue types and organs appear at the right place in the right time during embryogenesis. Regulation of morphogen synthesis, trafficking and diffusion are all known to play a part in setting up these gradients, and a complex web of signaling mechanisms ensures that specific responses occur at the correct threshold concentration in the recipient cells whose fate depends on these morphogens.

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Editorial
Cold Spring Harbor Laboratory Press,U.S.
Año de publicación
2010
Idioma
Inglés
ISBN 10 
0879698810
ISBN 13 
9780879698812
Encuadernación
Tapa dura
Número de edición
1
Número de páginas
900
Editor
Briscoe James, Vincent Jean-Paul, Lawrence Peter
Contacto del fabricante
no disponible
Persona responsable
no disponible