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Sinopsis
Genetic Variation: A Laboratory Manual is the first compendium of protocols specifically geared towards genetic variation studies, and includes thorough discussions on their applications for human and model organism studies. Intended for graduate students and professional scientists in clinical and research settings, it covers the complete spectrum of genetic variation—from SNPs and microsatellites to more complex DNA alterations, including copy number variation. Written and edited by leading scientists in the field, the early sections of the manual are devoted to study design and generating genotype data, the use of resources such as HapMap and dbSNP, as well as experimental, statistical, and bioinformatic approaches for analyzing the data. The final sections include descriptions of genetic variation in model organisms and discussions of recent insights into human genetic ancestry, forensics, and human variation.
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Críticas
Not only did this editorial team assemble an impressive group of accomplished scientists as authors, but they produced a book of broad scope, covering a wide range of topics. In fact, it is the amazing breadth of this book that will ensure its relevance for some time to come. This manual is relevant on many different levels and will no doubt provide any interested reader with a wealth of useful information. I for one have added this book to my collection of references on carrying out genetic studies on the underlying causes of disease and drug response in human and mouse populations. Nature Genetics This is an edited volume that seeks to provide specialists with a guide to the study of genetic variation in the age of genomics. It will be most appealing to anyone studying human genetic variation since this is the primary area of coverage, although other model systems are touched upon. A strength of the book is its conciseness, which is achieved by limiting the contents to basic introductions of the issues and citing more comprehensive references. --The Quarterly Review of Biology
Reseña del editor
Genetic Variation: A Laboratory Manual is the first compendium of protocols specifically geared towards genetic variation studies, and includes thorough discussions on their applications for human and model organism studies. Intended for graduate students and professional scientists in clinical and research settings, it covers the complete spectrum of genetic variation—from SNPs and microsatellites to more complex DNA alterations, including copy number variation. Written and edited by leading scientists in the field, the early sections of the manual are devoted to study design and generating genotype data, the use of resources such as HapMap and dbSNP, as well as experimental, statistical, and bioinformatic approaches for analyzing the data. The final sections include descriptions of genetic variation in model organisms and discussions of recent insights into human genetic ancestry, forensics, and human variation.
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Genetic Variation: A Laboratory Manual
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Cold Spring Harbor Laboratory Pr, 2007
ISBN 10: 0879697806
ISBN 13: 9780879697808
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Genetic Variation: A Laboratory Manual
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Taschenbuch. Condición: Wie neu. Gebraucht - Wie neu -This is the first compendium of protocols specifically geared towards genetic variation studies. It includes detailed step-by-step experimental protocols that cover the complete spectrum of genetic variation in humans and model organisms, along with advice on study design and analyzing data. Nº de ref. del artículo: 43286
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