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The TGF-B Family: v. 50 (Cold Spring Harbor Monograph Series) - Tapa dura

 
9780879697525: The TGF-B Family: v. 50 (Cold Spring Harbor Monograph Series)
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ISBN 10: 0879697520 ISBN 13: 9780879697525
Editorial: Cold Spring Harbor Laboratory Press, 2008

Sinopsis

Transforming growth factor-beta (TGF-ß) was identified about 27 years ago for its ability to induce phenotypic transformation of fibroblasts in diverse cell types. Following its cDNA cloning and the identification and characterization of various factors involved in hormonal control, tissue differentiation, and development, the existence of a large family of TGF-ß-related factors in all metazoa became apparent. TGF-ß is now considered as the prototype of this TGF-ß family, which in humans contains at least 35 family members, including activins, inhibins, bone morphogenetic proteins, growth/differentiation factors, and Müllerian inhibiting substance. This monograph comprehensively covers all aspects of the biology of TGF-ß and serves as a reference work for both specialists and researchers less familiar with the field.

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Reseña del editor

Transforming growth factor-beta (TGF-ß) was identified about 27 years ago for its ability to induce phenotypic transformation of fibroblasts in diverse cell types. Following its cDNA cloning and the identification and characterization of various factors involved in hormonal control, tissue differentiation, and development, the existence of a large family of TGF-ß-related factors in all metazoa became apparent. TGF-ß is now considered as the prototype of this TGF-ß family, which in humans contains at least 35 family members, including activins, inhibins, bone morphogenetic proteins, growth/differentiation factors, and Müllerian inhibiting substance. This monograph comprehensively covers all aspects of the biology of TGF-ß and serves as a reference work for both specialists and researchers less familiar with the field.

Críticas

The breadth and depth of the coverage of current TGF- b2; research is the most compelling feature of this book...[I]t is my recommendation that every principal investigator studying TGF- b2; should have a copy of this book...[T]he process of 'getting up to speed' becomes far less arduous. Development The book includes numerous figures and tables, which make each chapter accessible and pleasant to read. This volume will be of interest both for basic scientists concerned with topics such as transcriptional control of TFG- b2; signaling, as well as for translational scientists and clinicians focused on agents used to target the TGF- b2; signaling pathway...In summary, this book can be considered as a true TGF- b2; family encyclopedia. The Quarterly Review of Biology I found The TGF- b2; Family a great book. Tables and illustrations will surely prove useful in guiding the reader through complex problems and the book can be certainly recommended for teaching purposes. The clarity and comprehensiveness of the monograph, the eminence of the editors and authors, and the extensive bibliography at the end of each chapter make this book a 'must-have' reference for established investigators and clinicians and for newcomers attracted to TGF- b2; from various fields. Nature Cell Biology

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Editorial
Cold Spring Harbor Laboratory Press
Año de publicación
2008
Idioma
Inglés
ISBN 10 
0879697520
ISBN 13 
9780879697525
Encuadernación
Tapa dura
Número de edición
1
Número de páginas
1114
Editor
Derynck Rik, Miyazono Kohei
Contacto del fabricante
no disponible
Persona responsable
gpsr@libri.de
gpsr@libri.de

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