Principles of Population Genetics

3,96 valoración promedio
( 45 valoraciones por Goodreads )
 
9780878933082: Principles of Population Genetics

Principles of Population Genetics, Fourth Edition, is a thoroughly updated introduction to the field that is at last ascending to its rightful position of centrality to evolutionary genomics and human genetics. Rapid and inexpensive genotyping and sequencing have produced a profusion of data on genetic variation, along with a pressing need to inform students from many fields about the models that describe the underlying processes that give rise to observed patterns of genetic variation. This book provides a balanced presentation of theory and observation for students at the undergraduate and graduate levels as well as newcomers from fields like human genetics. The logical development of the models of population genetics encourages a deeper understanding of the principles, and the text has been rewritten with the goal to optimize its use as a teaching aid. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level. Integrated throughout the book are descriptions of molecular methods used to study variation in natural populations, as well as explanations of the relevant estimation theory using actual data.

Chapter 1 presents the fundamental observations and means for quantifying amounts and structure of genetic variation in natural populations. Chapter 2 gives a detailed examination of the implications of random mating for one locus and multiple loci and establishes the basic principles for thinking about mathematical models of variation. Chapter 3 presents the classic Wright-Fisher model as well as the coalescent approaches to random genetic drift. Chapter 4 adds mutation to models of drift and lays down the foundations for the neutral theory of molecular evolution. Natural selection in its many guises gets a thorough coverage in Chapter 5. Chapter 6 examines population subdivision and its consequences for the distribution of genetic variation among subpopulations, including the hierarchical F statistics used in estimating these effects. Molecular population genetics, including applications of coalescent theory, is the subject of Chapter 7. Evolutionary quantitative genetics is covered in Chapter 8, including an up-to-date treatment of the use of molecular markers for mapping and assisting in selection of quantitative characters. Chapter 9 is a new addition and covers the exciting field of population genomics, or the analysis of population genetic principles at a genome-wide scale. Finally, because of the explosion in genome-wide polymorphism data in humans and the realization that many problems in empirical population genetics need to be tuned to special, non-equilibrium circumstances of human populations, the authors devote Chapter 10 to human population genetics.

Applications of principles discussed in the text are illustrated with numerous examples of worked problems, using actual data. Many vital Web links are scattered throughout the text to connect the material to up-to-the-minute progress in this exciting field. Each chapter ends with a complete summary and offers several problems for solution, to reinforce and further develop the concepts.

"Sinopsis" puede pertenecer a otra edición de este libro.

About the Author:


Daniel L. Hartl is Higgins Professor of Biology in the Department of Organismic and Evolutionary Biology at Harvard University. His laboratory studies population genetics, genomics, and molecular evolution. He has been honored with the Samuel Weiner Outstanding Scholar Award and Medal, the Medal of the Stazione Zoologica Anton Dohrn, and is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences. He is also a Past President of the Genetics Society of America and the Society for Molecular Biology and Evolution. Hartl's Ph.D. was awarded by the University of Wisconsin, he did postdoctoral studies at the University of California in Berkeley, and he has been on the faculty of the University of Minnesota, Purdue University and Washington University Medical School in St. Louis. In addition to more than 300 scientific articles, Hartl has authored or coauthored 24 books.

Andrew G. Clark is Professor of Population Genetics in the Department of Molecular Biology and Genetics at Cornell University. Earning a Ph.D. in Population Genetics at Stanford University, he did postdoctoral work at Arizona State University and the University of Aarhus, Denmark, and a sabbatical at the University of California at Davis. Prior to joining the Cornell faculty in 2002, he was a professor in the Department of Biology at Pennsylvania State University. Dr. Clark's research focuses on the genetic basis of adaptive variation in natural populations, with emphasis on quantitative modeling of phenotypes as networks of interacting genes. He was elected Fellow of the American Association for the Advancement of Science in 1994, and serves on review panels for the NIH, NSF, and the Max Planck Society. He also served as President of the Society for Molecular Biology and Evolution, and is on the Advisory Council for the National Human Genome Research Institute.

Review:


"It is a pleasure to read this new edition of a classical textbook on population genetics. It shows very convincingly how population genetics has been revamped in the past twenty years by the introduction of new statistical and computational methods (in particular, coalescent theory), and the advent of genomic data, as well as how these developments changed a formerly rather arcane science and moved it toward the center of modern biology. In summary, the essence of population genetics is nicely condensed in this book. The presentation is wonderfully balanced between theory and observation, as well as classical and recent data sets and analysis tools."
--Wolfgang Stephan, The Quarterly Review of Biology


"Sobre este título" puede pertenecer a otra edición de este libro.

Comprar nuevo Ver libro

Gastos de envío: GRATIS
De Reino Unido a Estados Unidos de America

Destinos, gastos y plazos de envío

Añadir al carrito

Los mejores resultados en AbeBooks

1.

Daniel L. Hartl, Andrew G. Clark
Editorial: Sinauer Associates Inc.,U.S., United States (2007)
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Tapa dura Cantidad: 1
Librería
The Book Depository US
(London, Reino Unido)
Valoración
[?]

Descripción Sinauer Associates Inc.,U.S., United States, 2007. Hardback. Estado de conservación: New. 4th Revised edition. Language: English . Brand New Book. This thoroughly updated Fourth Edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level. Integrated throughout the book are descriptions of molecular methods used to study variation in natural populations, as well as explanations of the relevant estimation theory using actual data. Nº de ref. de la librería SPR9780878933082

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 89,17
Convertir moneda

Añadir al carrito

Gastos de envío: GRATIS
De Reino Unido a Estados Unidos de America
Destinos, gastos y plazos de envío

2.

Daniel L. Hartl; Andrew G. Clark
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Cantidad: 1
Librería
Speedy Hen LLC
(Sunrise, FL, Estados Unidos de America)
Valoración
[?]

Descripción Estado de conservación: New. Bookseller Inventory # ST0878933085. Nº de ref. de la librería ST0878933085

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 89,18
Convertir moneda

Añadir al carrito

Gastos de envío: GRATIS
A Estados Unidos de America
Destinos, gastos y plazos de envío

3.

Daniel L. Hartl, Andrew G. Clark
Editorial: Sinauer Associates Inc.,U.S., United States (2007)
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Tapa dura Cantidad: 1
Librería
The Book Depository
(London, Reino Unido)
Valoración
[?]

Descripción Sinauer Associates Inc.,U.S., United States, 2007. Hardback. Estado de conservación: New. 4th Revised edition. Language: English . Brand New Book. This thoroughly updated Fourth Edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level. Integrated throughout the book are descriptions of molecular methods used to study variation in natural populations, as well as explanations of the relevant estimation theory using actual data. Nº de ref. de la librería SPR9780878933082

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 91,11
Convertir moneda

Añadir al carrito

Gastos de envío: GRATIS
De Reino Unido a Estados Unidos de America
Destinos, gastos y plazos de envío

4.

Daniel L. Hartl, Andrew G. Clark
Editorial: Sinauer Associates, Inc. (2006)
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Tapa dura Cantidad: 1
Librería
Valoración
[?]

Descripción Sinauer Associates, Inc., 2006. Estado de conservación: New. 2006. 4th. Hardcover. This text introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level. Included are descriptions of molecular methods, as well as explanations of the relevant estimation theory using actual data. Num Pages: 545 pages, 175 illustrations. BIC Classification: PSAK. Category: (UU) Undergraduate. Dimension: 244 x 187 x 30. Weight in Grams: 1496. . . . . . . Nº de ref. de la librería V9780878933082

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 96,79
Convertir moneda

Añadir al carrito

Gastos de envío: GRATIS
De Irlanda a Estados Unidos de America
Destinos, gastos y plazos de envío

5.

Daniel L. Hartl
Editorial: Sinauer Associates
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Tapa dura Cantidad: 1
Librería
THE SAINT BOOKSTORE
(Southport, Reino Unido)
Valoración
[?]

Descripción Sinauer Associates. Hardcover. Estado de conservación: New. New copy - Usually dispatched within 2 working days. Nº de ref. de la librería B9780878933082

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 91,88
Convertir moneda

Añadir al carrito

Gastos de envío: EUR 7,60
De Reino Unido a Estados Unidos de America
Destinos, gastos y plazos de envío

6.

Hartl, Daniel L./ Clark, Andrew G.
Editorial: Sinauer Associates Inc (2006)
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Cantidad: > 20
Librería
Paperbackshop-US
(Wood Dale, IL, Estados Unidos de America)
Valoración
[?]

Descripción Sinauer Associates Inc, 2006. HRD. Estado de conservación: New. New Book. Shipped from US within 10 to 14 business days. Established seller since 2000. Nº de ref. de la librería VU-9780878933082

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 97,36
Convertir moneda

Añadir al carrito

Gastos de envío: EUR 3,39
A Estados Unidos de America
Destinos, gastos y plazos de envío

7.

Daniel L. Hartl, Andrew G. Clark
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Tapa dura Cantidad: 1
Librería
Ria Christie Collections
(Uxbridge, Reino Unido)
Valoración
[?]

Descripción Hardback. Estado de conservación: New. Not Signed; This thoroughly updated Fourth Edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level. Integrat. book. Nº de ref. de la librería ria9780878933082_rkm

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 96,56
Convertir moneda

Añadir al carrito

Gastos de envío: EUR 4,24
De Reino Unido a Estados Unidos de America
Destinos, gastos y plazos de envío

8.

Daniel L. Hartl, Andrew G. Clark
Editorial: Sinauer Associates, Inc.
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Tapa dura Cantidad: 1
Librería
Kennys Bookstore
(Olney, MD, Estados Unidos de America)
Valoración
[?]

Descripción Sinauer Associates, Inc. Estado de conservación: New. 2006. 4th. Hardcover. This text introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level. Included are descriptions of molecular methods, as well as explanations of the relevant estimation theory using actual data. Num Pages: 545 pages, 175 illustrations. BIC Classification: PSAK. Category: (UU) Undergraduate. Dimension: 244 x 187 x 30. Weight in Grams: 1496. . . . . . Books ship from the US and Ireland. Nº de ref. de la librería V9780878933082

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 103,81
Convertir moneda

Añadir al carrito

Gastos de envío: GRATIS
A Estados Unidos de America
Destinos, gastos y plazos de envío

9.

HARTL DANIEL L, ET AL
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Cantidad: 2
Librería
Bookshub
(Karol Bagh, India)
Valoración
[?]

Descripción Estado de conservación: New. New. US edition. Perfect condition. Customer satisfaction our priority. Nº de ref. de la librería ABE-FEB-70045

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 107,33
Convertir moneda

Añadir al carrito

Gastos de envío: GRATIS
De India a Estados Unidos de America
Destinos, gastos y plazos de envío

10.

HARTL DANIEL L, ET AL
ISBN 10: 0878933085 ISBN 13: 9780878933082
Nuevos Cantidad: 2
Librería
EBOOKSTORE2010
(New Delhi, ND, India)
Valoración
[?]

Descripción Estado de conservación: Brand New. New. US edition. Customer Satisfaction guaranteed!!. Nº de ref. de la librería SHUB70045

Más información sobre esta librería | Hacer una pregunta a la librería

Comprar nuevo
EUR 107,37
Convertir moneda

Añadir al carrito

Gastos de envío: GRATIS
De India a Estados Unidos de America
Destinos, gastos y plazos de envío

Existen otras copia(s) de este libro

Ver todos los resultados de su búsqueda