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9780849366949: Signal Transduction in Leukocytes: G Protein-Related and Other Pathways

Sinopsis

Signal Transduction in Leukocytes presents important principles and various aspects of cellular regulation in leukocytes. The book discusses receptor structure and signaling, emphasizing cytokine receptors and the T cell and B cell antigen receptors. It investigates the role of the heterotrimeric G proteins and small G proteins as transducers. Authorities in each field cover a wide range of topics. They explore propagation of signaling cascades through second messengers and serine/threonine kinases, the initiation of signaling from the B and T cell antigen receptors by tyrosine phosphorylation and protein recruitment, and the role of signaling in cell-cell interactions and the regulation of the cell cycle. The book outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages.

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Reseña del editor

Signal Transduction in Leukocytes presents important principles and various aspects of cellular regulation in leukocytes. The book discusses receptor structure and signaling, emphasizing cytokine receptors and the T cell and B cell antigen receptors. It investigates the role of the heterotrimeric G proteins and small G proteins as transducers.
Authorities in each field cover a wide range of topics. They explore propagation of signaling cascades through second messengers and serine/threonine kinases, the initiation of signaling from the B and T cell antigen receptors by tyrosine phosphorylation and protein recruitment, and the role of signaling in cell-cell interactions and the regulation of the cell cycle. The book outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages.

Contraportada

The term 'signal transduction' denotes the biochemical sequence of reactions that occurs as a cell responds to external stimuli. It comprises the initial step of hormone binding to a receptor, activation of transmembrane events, triggering of cytoplasmic reaction cascades, and generation of new proteins through which the appropriate cell responses (morphologic change, growth, differentiation, and cell-cell interactions) can take place.

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Lad, Pramod M.; Kaptein, John S.; Lin, Ching-Kow
Publicado por CRC Press, 1995
ISBN 10: 0849366941 ISBN 13: 9780849366949
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Librería: The Book Bin, Salem, OR, Estados Unidos de America

Calificación del vendedor: 5 de 5 estrellas Valoración 5 estrellas, Más información sobre las valoraciones de los vendedores

Hardcover. Condición: As New. Liker New, light shelf wear. Year 1996. 383pp. > Language: English | > Size: 8vo - over 7 3/4 in - 9 3/4 in Tall | > Media/Binding: Hardcover |. Nº de ref. del artículo: CORV-BBC-0K50467

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