Endothelin Receptors: From the Gene to the Human: 21 (Handbooks in Pharmacology and Toxicology) - Tapa dura

Libro 16 de 16: Handbooks in Pharmacology and Toxicology

Ruffolo Jr., Robert R.

 
9780849359385: Endothelin Receptors: From the Gene to the Human: 21 (Handbooks in Pharmacology and Toxicology)
Tapa dura
ISBN 10: 0849359384 ISBN 13: 9780849359385
Editorial: CRC Press, 1995

Sinopsis

Since the discovery of endothelin, major advances have been made in understanding the molecular structure and function of the endothelin receptors. At least two subtypes of receptors, designated ETA and ETB, have been identified through biochemical and pharmacological techniques. These subtypes are cloned and expressed and additional subtypes appear to exist. The biochemical events involved in the signal transduction processes that ultimately activate the cellular machinery involved in the end-organ responses are presented, as are the mechanisms by which the receptors recognize specific and different G-proteins. Functions mediated by the receptors at the cellular, tissue and, organ level are reviewed in detail, as well as the roles that they may play a part in the physiologic and pathophysiologic processes in animals and in humans. This book is unique in its breadth of scope. The most recent and important advances, from the intracellular level of the nucleus to the functional effect that endothelin receptors mediate in intact organs, are compiled and reviewed.

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Acerca del autor

Robert R. Ruffolo Jr.

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
CRC Press
Año de publicación
1995
Idioma
Inglés
ISBN 10 
0849359384
ISBN 13 
9780849359385
Encuadernación
Tapa dura
Número de edición
1
Número de páginas
304
Contacto del fabricante
no disponible
Persona responsable
no disponible