Enzyme Functionality serves as a conduit for trailblazing research in enzyme engineering-relating current understanding of sequence families, the new notion of enzyme structure classes, and modern methods in protein engineering, design, and directed evolution to accelerate the development of novel enzyme functionalities. This reference gathers the diverse perspectives of nearly 80 scientists from around the globe and surveys all leading rational and random approaches to the artificial evolution of enzymes. Citing more than 1500 notable works, it outlines assays for enzyme activity, stability, and specificity and a wide variety of site-directed, redesign, and evolutionary engineering methods.
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Allan Svendsen is Senior Science Manager of Protein Design at Novozymes A/S, Bagsvaerd, Denmark. The author or coauthor of more than 80 scientific publications, he holds more than 60 patent applications and patents in protein engineering. An organizer of several global conferences on lipases and lipids, and coordinator of several international engineering projects, Mr. Svendsen received the Cand. Scient. degree (1985) in biochemistry from the Institute of Biochemical Genetics, University of Copenhagen, Denmark.
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