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Excitation-Contraction Coupling and Cardiac Contractile Force: 237 (Developments in Cardiovascular Medicine, 237) - Tapa dura
Sinopsis
How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern `portrait’ of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction.
The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure).
Excitation-Contraction Coupling and Cardiac Contractile Force &endash; Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.
"Sinopsis" puede pertenecer a otra edición de este libro.
Críticas
`Since the first edition of Excitation-Contraction Coupling and Cardiac Contractile Force was published 10 years ago, it has become a classic. The second edition is stunning. It retains the zest and compact form of the first edition, contains the wealth of information and analysis that has become the Bers' hallmark and is well written. It is easy and delightful to read.'
W. Jonathan Lederer (excerpted from the Introduction).
`This second edition of a now classical text is both extensively revised and up-to-date. The many illustrations, a large number of which are new to this edition, supplement a clearly written text that is filled with useful information. For those who seek a lucid, comprehensive and authoritative description of the interlocked systems that control the heart beat, I know of no other source that approaches Bers' Excitation-Contraction Coupling and Cardiac Contractile Force.'
Arnold M. Katz
`This book is a breath of fresh (and educated and thoughtful and well-organized) air Don Bers has produced a remarkably approachable and informative volume, clearly superior to others in this field. Active researchers should buy this book for themselves and their students.'
Laurence L. Brunton
Reseña del editor
How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction.
The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure).
Excitation-Contraction Coupling and Cardiac Contractile Force &endash; Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.
"Sobre este título" puede pertenecer a otra edición de este libro.
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Excitation-Contraction Coupling and Cardiac Contractile Force (Developments in Cardiovascular Medicine, 237)
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Excitation-Contraction Coupling and Cardiac Contractile Force (Developments in Cardiovascular Medicine, 237)
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Excitation-Contraction Coupling and Cardiac Contractile Force
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Excitation-Contraction Coupling and Cardiac Contractile Force (Hardcover)
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Kluwer Academic Publishers, Dordrecht, 2001
ISBN 10: 0792371577
ISBN 13: 9780792371571
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Hardcover. Condición: new. Hardcover. How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation--contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation--contraction coupling.A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation--calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation--Contraction Coupling and Cardiac Contractile Force -- Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.`Since the first edition of Excitation--Contraction Coupling and Cardiac Contractile Force was published 10 years ago, it has become a classic. The second edition is stunning. It retains the zest and compact form of the first edition, contains the wealth of information and analysis that has become the Bers' hallmark and is well written. It is easy and delightful to read.' W. Jonathan Lederer (excerpted from the Introduction). `This second edition of a now classical text is both extensively revised and up-to-date. The many illustrations, a large number of which are new to this edition, supplement a clearly written text that is filled with useful information. For those who seek a lucid, comprehensive and authoritative description of the interlocked systems that control the heart beat, I know of no other source that approaches Bers' Excitation--Contraction Coupling and Cardiac Contractile Force.' Arnold M. Katz. `This book is a breath of fresh (and educated and thoughtful and well-organized) air Don Bers has produced a remarkably approachable and informative volume, clearly superior to others in this field. Active researchers should buy this book for themselves and their students.'Laurence L. Brunton. Offers a portrait of how the heart works and shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. This book considers the cellular structures involved in excitation-contraction coupling. It is intended for students of the cardiovascular system at various levels from such as medical students. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Nº de ref. del artículo: 9780792371571
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Excitation-Contraction Coupling and Cardiac Contractile Force
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Gebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking abo. Nº de ref. del artículo: 5969960
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Excitation-Contraction Coupling and Cardiac Contractile Force (Developments in Cardiovascular Medicine, 237)
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Excitation-Contraction Coupling and Cardiac Contractile Force
Publicado por
Springer Netherlands Aug 2001, 2001
ISBN 10: 0792371577
ISBN 13: 9780792371571
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -How is the heartbeat generated What controls the strength of contraction of heart muscle What are the links between cardiac structure and function How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart Are there important species differences in how contraction is regulated in the heart How do the new molecular data fit together in understanding the heart beat What goes wrong in ischemia, hypertrophy, and heart failure This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation-Contraction Coupling and Cardiac Contractile Force &endash; Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields. 454 pp. Englisch. Nº de ref. del artículo: 9780792371571
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Excitation-Contraction Coupling and Cardiac Contractile Force
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Springer Netherlands, Springer Netherlands Aug 2001, 2001
ISBN 10: 0792371577
ISBN 13: 9780792371571
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Buch. Condición: Neu. Neuware -How is the heartbeat generated What controls the strength of contraction of heart muscle What are the links between cardiac structure and function How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart Are there important species differences in how contraction is regulated in the heart How do the new molecular data fit together in understanding the heart beat What goes wrong in ischemia, hypertrophy, and heart failure This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction.The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure).Excitation-Contraction Coupling and Cardiac Contractile Force &endash; Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 454 pp. Englisch. Nº de ref. del artículo: 9780792371571
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Excitation-Contraction Coupling and Cardiac Contractile Force
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