Diseases of the Skin: An Outline of the Principles and Practice of Dermatology (Classic Reprint) - Tapa dura

Sinopsis

Excerpt from Diseases of the Skin: An Outline of the Principles and Practice of Dermatology

The first step in recovery from inflammation is the cessation of stasis iollowed by restoration of the blood circulation. Before stasis disappears, however, hemo globin, or red blood-corpuscles, frequently escape from a capillary into the surrounding tissue, with the result that pigmentation of a more or less permanent charac ter is left behind. According to Virchow, the pigment is always derived from the blood, and is at first held in solution in the plasma which bathes the tissues. The pigment appears to be derived from certain special mmoblastic cells, to which Ehrmann gives the name of mm. The majority of observers agree that melanin, which can be distinguished from hemato genous pigments by morphological and chemical tests, has its origin in the blood, the pigment-bearing cells or chromatophores being variously regarded as connec tive - timue cells (unna, Kelliker), leucocytes (schmidt), or protoplasmic processes from epithelial cells (kro mayer). Other writers (kaposi, Delépine) hold that melanin is not a degeneration product of hemoglobin, but a separation or secretion product of the protoplasm oi pigmented cells.'

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