Organic Synthesis: The Disconnection Approach

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9780470712368: Organic Synthesis: The Disconnection Approach

One approach to organic synthesis is retrosynthetic analysis With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules Reversing this process gives a synthetic route to the target molecule from simpler starting materials This disconnection approach to synthesis is now a fundamental part of every organic synthesis course Organic Synthesis The Disconnection Approach 2nd Edition introduces this important technique to help students to design their own organic syntheses There are forty chapters those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups The strategy chapters cover questions of selectivity protection stereochemistry and develop more advanced thinking via reagents specifically designed for difficult problems Examples are drawn from pharmaceuticals agrochemicals natural products pheromones perfumery and flavouring compounds dyestuffs monomers and intermediates used in more advanced synthetic work Reasons for wishing to synthesise each compound are given This second edition has been fully revised and updated with a modern look Recent examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel Organic Synthesis Strategy and Control Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry Organic Synthesis The Disconnection Approach 2nd edition provides a full course in retrosynthetic analysis for chemistry and biochemistry students and a refresher for organic chemists working in industry and academia

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A workbook providing additional examples, problems, and solutions for use with Warren's Organic Synthesis: The Disconnection Approach. Exercises correspond to chapters in the main text. Problems of special ease or difficulty are labeled for optional use. Workbook includes a formula index of all target molecules contained in the text and workbook.

From the Back Cover:

Workbook for Organic Synthesis: The Disconnection Approach Stuart Warren, Department of Chemistry and Churchill College, Cambridge University This workbook provides an extra set of examples to support the text Organic Synthesis: The Disconnection Approach, as described below. Each example is analysed in the same way as those in the main text with disconnections followed by synthesis, allowing the student to explore a wider range of types of target molecule and synthetic method. The main function of the workbook is, however, to provide a graded series of problems which extend the student's experience of the types of molecules being synthesised by organic chemists. These, together with the examples, are classified into the same 40 chapters as the main text so that it is possible to use them in conjunction with it. Each problem is followed by a suggested solution or solutions analysed in the same way as the examples and no methodology other than that introduced in the main text is required. Examples and problems are interspersed to provide a developing chain of argument. Organic Synthesis: The disconnection Approach The book will help students to design their own organic synthesis, giving a wide coverage of synthetic-methods. The disconnection approach is used throughout so that starting materials are chosen after analysing the structure of the target molecules. There are forty chapters: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The instrumental chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The number and position of these functional groups provides the classification for these chapters. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specially designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. The book will also assist more experienced chemists who feel they are out of touch with present day thinking on the subject.

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Stuart Warren, Paul Wyatt
Editorial: John Wiley and Sons Ltd, United States (2009)
ISBN 10: 0470712368 ISBN 13: 9780470712368
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Descripción John Wiley and Sons Ltd, United States, 2009. Paperback. Estado de conservación: New. 2nd Edition. Language: English . Brand New Book. One approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This disconnection approach to synthesis is now a fundamental part of every organic synthesis course. Organic Synthesis: The Disconnection Approach, 2nd Edition introduces this important technique, to help students to design their own organic syntheses. There are forty chapters: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. This second edition has been fully revised and updated with a modern look. Recent examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control . Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Organic Synthesis: The Disconnection Approach, 2nd edition provides a full course in retrosynthetic analysis for chemistry and biochemistry students and a refresher for organic chemists working in industry and academia. Nº de ref. de la librería AAZ9780470712368

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Stuart Warren, Paul Wyatt
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Descripción John Wiley and Sons Ltd, United States, 2009. Paperback. Estado de conservación: New. 2nd Edition. Language: English . Brand New Book. One approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This disconnection approach to synthesis is now a fundamental part of every organic synthesis course. Organic Synthesis: The Disconnection Approach, 2nd Edition introduces this important technique, to help students to design their own organic syntheses. There are forty chapters: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. This second edition has been fully revised and updated with a modern look. Recent examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control . Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Organic Synthesis: The Disconnection Approach, 2nd edition provides a full course in retrosynthetic analysis for chemistry and biochemistry students and a refresher for organic chemists working in industry and academia. Nº de ref. de la librería AAZ9780470712368

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Descripción Wiley 2008-11-21, Oxford, 2008. paperback. Estado de conservación: New. Nº de ref. de la librería 9780470712368

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Descripción John Wiley and Sons Ltd, 2008. Estado de conservación: New. 2008. 2nd. Paperback. One approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. Num Pages: 344 pages, illustrations. BIC Classification: PNN. Category: (P) Professional & Vocational. Dimension: 192 x 248 x 19. Weight in Grams: 652. . . . . . . Nº de ref. de la librería V9780470712368

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Descripción John Wiley and Sons Ltd. Estado de conservación: New. 2008. 2nd. Paperback. One approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. Num Pages: 344 pages, illustrations. BIC Classification: PNN. Category: (P) Professional & Vocational. Dimension: 192 x 248 x 19. Weight in Grams: 652. . . . . . Books ship from the US and Ireland. Nº de ref. de la librería V9780470712368

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