THIS BOOK DESCRIBES THE PRINCIPLES, METHODS, AND APPLICATIONS OF PBPK MODELING IN THE PHARMACEUTICAL INDUSTRY. IT ADDRESSES A GROWING NEED, AS MORE AND MORE PHARMA COMPANIES ARE INTEGRATING PBPK INTO THEIR LEAD SELECTION CYCLE AND CLINICAL DEVELOPMENT. MOVING EASILY FROM THEORY TO PRACTICE, THE AUTHOR PRESENTS COVERAGE OF BOTH THE PRINCIPLES AND APPLICATIONS OF PBPK MODELING, EXPOSING THE POWER OF THIS TOOL TO IMPROVE THE PROCESS OF DRUG DISCOVERY AND DEVELOPMENT. WITH END–OF–CHAPTER GLOSSARIES, EXTENSIVE BIBLIOGRAPHIC REFERENCES, AND AN EMPHASIS ON PRACTICAL APPLICATIONS, THIS RESOURCE PROVIDES A MUCH–NEEDED SINGLE SOURCE FOR THIS IMPORTANT AREA.
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Críticas:
There is little to fault the book. ... [it] should be on the shelf and a companion to anyone seriously interested in mechanistic model-based drug development. (Nature CPT, 10 July 2013) Peters does a credible job of bringing this huge area of complex physiology and mathematics together. (Pharmaceutical Journal, 21 July 2012)
Reseña del editor:
This book describes the principles, methods, and applications of PBPK modeling in the pharmaceutical industry. It addresses a growing need, as more and more pharma companies are integrating PBPK into their lead selection cycle and clinical development. Moving easily from theory to practice, the author presents coverage of both the principles and applications of PBPK modeling, exposing the power of this tool to improve the process of drug discovery and development. With end-of-chapter glossaries, extensive bibliographic references, and an emphasis on practical applications, this resource provides a much-needed single source for this important area.
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- EditorialWiley
- Año de publicación2012
- ISBN 10 0470484063
- ISBN 13 9780470484067
- EncuadernaciónTapa dura
- Número de páginas450