This handbook is the definitive manual for producing a Cochrane systematic review. The editors have drawn from the expertise of the Cochrane methods groups to bring together the breadth and depth of systematic reviewing experience in a step by step guide to writing a Cochrane review. Anyone conducting a systematic review will be interested in Cochrane methodology, which represents the 'gold standard' in the science of reviewing. "The Cochrane Handbook for Systematic Reviews of Interventions" is divided into two sections. Section A deals with the basics, and is compulsory reading for all review authors. Section B contains more specialist topics.Topics include addressing risk of bias in included studies, analysing and presenting results (including publication bias), using individual patient data, prospective meta analysis, qualitative methods, and incorporating economic evaluation. "The Cochrane Handbook for Systematic Reviews of Interventions" is essential reading for every Cochrane review author. It is also of interest for authors of non Cochrane systematic reviews, clinical trial authors, Health Technology Assessment and Health Economics organisations.
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