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Sinopsis
Our understanding of the mechanisms regulating gene expression, which determine the patterns of growth and development in all living organisms, ultimately involves the elucidation of the detailed and dy namic interactions of proteins with nucleic acids -both DNA and RNA. Until recently the commonly presented view of the DNA double helix as visualized on the covers of many textbooks and journals - was as a monotonous static straight rod incapable in its own right of directing the processes necessary for the conservation and selective reading of genetic information. This view, although perhaps extreme, was reinforced by the necessary linearity of genetic maps. The reality is that the biological functions of both DNA and RNA are dependent on complex, and sometimes transient, three-dimensional nucleoprotein structures in which genetically distant elements are brought into close spatial proximity. It is in such structures that the enzymatic manipulation of DNA in the essential biological processes as DNA replication, transcription and recombination are effected - the complexes are the mediators of the 'DNA transactions' of Hatch Echols.
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Críticas
The value of this analysis is found in the insight it provides into the mechanism of complex systems.... the text is generally well-written and flows smoothly. [this work] is full of insights and stimulating in its unification of structure and function, a perspective that is increasingly inmportant in molecular biology. Trends in Genetics; Andrew Travers has done an excellent job of selecting examples illustrating the central theme of the book...the figures are instructive, well designed and selected...I wholeheartedly recommend this book for all structural and molecular biologists who are interested in the biological role of DNA - Trends in Biochemical Sciences; ...the book does bring together areas in a juxtaposition unique to its author...explained with the authority one would expect from Travers. - Nature; ...the book quickly takes us beyond the straightforward undergraduate texts, to provide a helpful source of information and discussion material for advanced undergraduate or Masters'courses. Journal of Biological Education; The value of this analysis is found in the insight it provides into the mechanism of complex systems.... the text is generally well-written and flows smoothly. [this work] is full of insights and stimulating in its unification of structure and function, a perspective that is increasingly r portant in molecular biology. Trends in Genetics; Overall, this is a densely detailed text and worth its place on the shelf of practitioners in the field who wish to maintain an overall view...gathers together current knowledge in a useful way - Current Biology
Reseña del editor
Our understanding of the mechanisms regulating gene expression, which determine the patterns of growth and development in all living organisms, ultimately involves the elucidation of the detailed and dy namic interactions of proteins with nucleic acids -both DNA and RNA. Until recently the commonly presented view of the DNA double helix as visualized on the covers of many textbooks and journals - was as a monotonous static straight rod incapable in its own right of directing the processes necessary for the conservation and selective reading of genetic information. This view, although perhaps extreme, was reinforced by the necessary linearity of genetic maps. The reality is that the biological functions of both DNA and RNA are dependent on complex, and sometimes transient, three-dimensional nucleoprotein structures in which genetically distant elements are brought into close spatial proximity. It is in such structures that the enzymatic manipulation of DNA in the essential biological processes as DNA replication, transcription and recombination are effected - the complexes are the mediators of the 'DNA transactions' of Hatch Echols.
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DNA-Protein Interactions
Publicado por
Springer Netherlands, 1993
ISBN 10: 0412259907
ISBN 13: 9780412259906
Antiguo o usado
Tapa blanda
Librería: Better World Books Ltd, Dunfermline, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
Condición: Good. Ships from the UK. Former library book; may include library markings. Used book that is in clean, average condition without any missing pages. Softcover reprint of the original 1st ed. 1993. Nº de ref. del artículo: GRP17161604
Cantidad disponible: 1 disponibles
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DNA-Protein Interactions
Publicado por
Chapman & Hall, 1993
ISBN 10: 0412259907
ISBN 13: 9780412259906
Antiguo o usado
Tapa blanda
Librería: Anybook.com, Lincoln, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
Condición: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,350grams, ISBN:9780412259906. Nº de ref. del artículo: 8687194
Cantidad disponible: 1 disponibles
Imagen de archivo
DNA-Protein Interactions
Publicado por
Chapman & Hall, 1993
ISBN 10: 0412259907
ISBN 13: 9780412259906
Antiguo o usado
Tapa blanda
Librería: Anybook.com, Lincoln, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
Condición: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Clean from markings. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,350grams, ISBN:0412259907. Nº de ref. del artículo: 8655930
Cantidad disponible: 1 disponibles
Imagen de archivo
DNA-Protein Interactions
Publicado por
Chapman & Hall, 1993
ISBN 10: 0412259907
ISBN 13: 9780412259906
Antiguo o usado
Tapa blanda
Librería: Anybook.com, Lincoln, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
Condición: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Clean from markings. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,400grams, ISBN:9780412259906. Nº de ref. del artículo: 9879512
Cantidad disponible: 1 disponibles
Imagen de archivo
DNA-Protein Interactions
Publicado por
Chapman & Hall, 1993
ISBN 10: 0412259907
ISBN 13: 9780412259906
Antiguo o usado
Tapa blanda
Librería: Anybook.com, Lincoln, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
Condición: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Clean from markings. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,350grams, ISBN:9780412259906. Nº de ref. del artículo: 9856259
Cantidad disponible: 1 disponibles
Imagen de archivo
DNA-Protein Interactions
Publicado por
Chapman & Hall, 1993
ISBN 10: 0412259907
ISBN 13: 9780412259906
Antiguo o usado
Tapa blanda
Librería: Anybook.com, Lincoln, Reino Unido
Calificación del vendedor: 5 de 5 estrellas
Condición: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. Clean from markings. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,350grams, ISBN:9780412259906. Nº de ref. del artículo: 9815445
Cantidad disponible: 1 disponibles
Imagen de archivo
DNA-Protein Interactions
Publicado por
Springer Netherlands, 1993
ISBN 10: 0412259907
ISBN 13: 9780412259906
Antiguo o usado
Tapa blanda
Librería: Better World Books, Mishawaka, IN, Estados Unidos de America
Calificación del vendedor: 5 de 5 estrellas
Condición: Good. Used book that is in clean, average condition without any missing pages. Softcover reprint of the original 1st ed. 1993. Nº de ref. del artículo: 39127887-6
Cantidad disponible: 1 disponibles
Imagen de archivo
DNA-Protein Interactions
Publicado por
Springer Netherlands, 1993
ISBN 10: 0412259907
ISBN 13: 9780412259906
Antiguo o usado
Tapa blanda
Librería: Better World Books, Mishawaka, IN, Estados Unidos de America
Calificación del vendedor: 5 de 5 estrellas
Condición: Good. Former library book; may include library markings. Used book that is in clean, average condition without any missing pages. Softcover reprint of the original 1st ed. 1993. Nº de ref. del artículo: GRP17161604
Cantidad disponible: 1 disponibles
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DNA-Protein Interactions
Librería: Wonder Book, Frederick, MD, Estados Unidos de America
Calificación del vendedor: 5 de 5 estrellas
Condición: Good. Good condition. A copy that has been read but remains intact. May contain markings such as bookplates, stamps, limited notes and highlighting, or a few light stains. Bundled media such as CDs, DVDs, floppy disks or access codes may not be included. Nº de ref. del artículo: C04J-00191
Cantidad disponible: 1 disponibles
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DNA-Protein Interactions.
Publicado por
Springer, Berlin, 1993
ISBN 10: 0412259907
ISBN 13: 9780412259906
Antiguo o usado
brosch.
Librería: Bücher bei den 7 Bergen, Sibbesse, Alemania
Calificación del vendedor: 5 de 5 estrellas
brosch. Condición: Gut. 192 S., gr. 8°, Ill. Etwas berieben, sonst guter Zustand. FL1058 Sprache: Englisch Gewicht in Gramm: 330. Nº de ref. del artículo: 134370
Cantidad disponible: 1 disponibles