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Oncogenes: An Introduction to the Concept of Cancer Genes - Tapa blanda

Edison T. Liu, Kathy B. Burck

 
9780387964232: Oncogenes: An Introduction to the Concept of Cancer Genes
Tapa blanda
ISBN 10: 0387964231 ISBN 13: 9780387964232
Editorial: Springer New York, 1988

Sinopsis

"Cancer viruses" have played a paradoxical role in the history of cancer research.

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Reseña del editor

"Cancer viruses" have played a paradoxical role in the history of cancer research. Discovered in 1911 by Peyton Rous (1) at the Rockefeller Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campaign to focus attention on viruses as etiological agents in cancer, his plat­ form having been the chemical characterization of the tobacco mosaic virus as a pure protein-correction, ribonucleoprotein-in 1935 (2). This doctrine was a centerpiece of the U.S. National Cancer Crusade of 1971: if human cancers were caused by viruses, the central task was to isolate them and prepare vaccines for immunization. At that point, many observers felt that perhaps too much attention was being devoted to cancer viruses. It was problematic whether viruses played an etiological role in more than a handful of human cancers.

Reseña del editor

This topical, handy volume is the perfect guide for physicians or scientists not specializing in the field, but wishing to understand exciting recent developments in cellular and molecular biology relevant to oncogene research. The terminology used in discussing oncogenes and their products is straightforwardly defined, and the concepts crucial to an understanding of oncogene research are clearly presented. Key topics are explored, including assay techniques used in molecular biology; methods for assessing behavior of normal genes and oncogenes; DNA and RNA tumor viruses; viruses inducing immunodeficiency; cellular proto-oncogenes and their relation to retroviral oncogenes; and possible roles of gene amplification and mutation, chromosomal translocation, and cellular growth factors in human cancer. An up-to-date survey of research on the major oncogenes and a discussion of the possibilities for future diagnostic and therapeutic applications of oncogene research are provided. The presentation is enhanced through many original illustrations, an appendix on oncogenes and related genes, and an up-to-date bibliography.

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Editorial
Springer New York
Año de publicación
1988
Idioma
Inglés
ISBN 10 
0387964231
ISBN 13 
9780387964232
Encuadernación
Tapa blanda
Número de edición
1
Número de páginas
320
Contacto del fabricante
no disponible
Persona responsable
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

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