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The Somatotrophic Axis and the Reproductive Process in Health and Disease (Serono Symposia USA) - Tapa dura

 
9780387944197: The Somatotrophic Axis and the Reproductive Process in Health and Disease (Serono Symposia USA)
Tapa dura
ISBN 10: 0387944192 ISBN 13: 9780387944197
Editorial: Springer-Verlag New York Inc., 1995

Sinopsis

This volume contains the proceedings of the Symposium on The Somatotrophic Axis and the Reproductive Process in Health and Disease, held October 28 - 31, 1993 in Baltimore, Maryland. Written and edited by eminent international experts, the papers herein cover: the state-of-the-art on growth hormone and its receptor; pubertal, menstrual, gestational, and menopausal adaptation; growth hormone and the ovarian connection; potential utility of growth hormone in clinical reproductive medicine; and the potential utility of growth hormone in ovulation induction.

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Reseña del editor

For many years now, our understanding of the somatotrophic and reproduc­ tive axes has evolved essentially independently, both fields of study reaching a highly advanced, although far from complete, level of under­ standing. Along the way, however, it became apparent that in some circumstances the reproductive and somatotrophic axes may be inter­ dependent. Inklings to this effect were at times feeble and at other times more convincing. Among those inklings are the clinical recognition by pediatric endocrinologists of the apparent association between isolated GH deficiency and delayed puberty, as well as of the apparent permissive, pUberty-promoting property of GH. Equally important is a body of experi­ mental studies establishing the ovary of multiple species as a site of GH reception and action. Arguing against an essential role for GH in the reproductive process is the observation that individuals who have GH resistance of the Laron variety are fertile arid that isolated GH deficiency does not constitute an absolute barrier to the attainment of sexual maturation and fertility. The intraovarian insulin-like growth factor (IGF) hypothesis proposes that IGFs may serve as amplifiers of gonadotropin action. Although the dependence of intraovarian IGFs on systemic GH action has never been unequivocally demonstrated, that leap of faith has often been made. The intraovarian IGF hypothesis serves as the rationale for the adjunctive use of GH in the induction of ovulation.

Reseña del editor

This volume contains the proceedings of the Symposium on The Somatotrophic Axis and the Reproductive Process in Health and Disease, held October 28 - 31, 1993 in Baltimore, Maryland. Written and edited by eminent international experts, the papers herein cover: the state-of-the-art on growth hormone and its receptor; pubertal, menstrual, gestational, and menopausal adaptation; growth hormone and the ovarian connection; potential utility of growth hormone in clinical reproductive medicine; and the potential utility of growth hormone in ovulation induction.

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Editorial
Springer-Verlag New York Inc.
Año de publicación
1995
Idioma
Inglés
ISBN 10 
0387944192
ISBN 13 
9780387944197
Encuadernación
Tapa dura
Número de páginas
350
Editor
Adashi Eli Y., Thorner Michael O.
Contacto del fabricante
ROXIO
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