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Growth Hormone II: Basic & Clinical Aspects (Proceedings in the Serono Symposia, USA) - Tapa dura

Bercu, Barry B.; Bercu, B.

 
9780387941332: Growth Hormone II: Basic & Clinical Aspects (Proceedings in the Serono Symposia, USA)
Tapa dura
ISBN 10: 0387941339 ISBN 13: 9780387941332
Editorial: SPRINGER NATURE, 1994

Reseña del editor

This book is a compendium of proceedings from the Symposium on Growth Hormone II: Basic and Clinical Aspects. The intent of the sym­ posium was to review current aspects of the rapidly expanding science of growth hormone (GH) neuroendocrinology, especially those develop­ ments that occurred since our last meeting in 1985. The meeting was timely since there have been many new and exciting developments in basic research on the GH axis, and several new clinical applications for GH other than growth have been identified. For example, significant strides have been made into use of the bioengineered hormone as an anabolic in debilitated states and as an immunorestorative agent. Both these areas have received most attention as they relate to geriatric popu­ lations. Furthermore, recent focus on a novel family of GH secretagogues that complement the action of GHRH has shown that in animal models, these compounds have the potential to restore GH secretion in deficient or insufficient states, including growth retardation, obesity, and aging. Accordingly, these xenobiotics may have significant potential as drug products to stimulate physiological GH secretion and, thus, resist or reverse some of the maladaptive changes in form and function resulting from GH insufficiency. The importance of these agents as drug candidates is underscored by the diversity of molecules that have been studied by various pharmaceutical companies and the recent discovery that non­ peptide analogs with high oral bioavailability can be synthesized.

Reseña del editor

This volume contains the proceedings of the Second International Symposium on Growth Hormone (GH): Basic and Clinical Aspects, held in December 1992 to review current aspects of the rapidly expanding science of GH neuroendocrinology. The authors first present a background of neuroendocrine regulatory processes incorporating the roles of GHRH and somatostatin (SRIF) as major controllers of GH secretion. The book then proceeds to discuss the most recent information on the cellular and molecular mechanisms by which these compounds regulate GH secretion non-growth functions of GH, with major focus on GH and immune function generalized effects of GH in the aged GH insufficiency structural and functional analyses of GH secretagogues and current clinical studies involving GH.

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Editorial
SPRINGER NATURE
Año de publicación
1994
Idioma
Inglés
ISBN 10 
0387941339
ISBN 13 
9780387941332
Encuadernación
Tapa dura
Número de páginas
379
Editor
Bercu Barry B.
Contacto del fabricante
no disponible
Persona responsable
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