Receptor - Based Drug Design: 89 (Drugs and the Pharmaceutical Sciences) - Tapa blanda

 
9780367400521: Receptor - Based Drug Design: 89 (Drugs and the Pharmaceutical Sciences)
Tapa blanda
ISBN 10: 0367400529 ISBN 13: 9780367400521
Editorial: CRC Press, 2019

Sinopsis

Employing a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels, this detailed, single-source reference illustrates the principles of pharmacological analysis and receptor classification that are the basis of rational drug design.
Explains the experimental and theoretical methods used to characterize interactions between ligands and receptors-providing the pharmacological information needed to solve treatment problems and facilitate the drug design process!
Demonstrating the achievements of the receptor-based approach in therapeutics and indicating future directions, Receptor-Based Drug Design

  • introduces novel computer-assisted strategies for the design of new agonists, antagonists, and inverse agonists for G-protein-coupled receptors
  • shows how to assess agonist concentration-effect curve data
  • discusses radioligand binding assays
  • presents new in vitro multiarray assays for G-protein-coupled receptors
  • explains the use of individual second messenger signaling responses in analyzing drug-receptor interactions
  • examines the role of electrophysiology in finding new drugs and drug targets
  • describes selectively acting b-adrenoceptor agonists and glucocorticoid steroids for asthma treatment
  • outlines the rationale for using angiotensin receptor antagonists
  • and more!
    Written by over 25 international authorities and containing nearly 1200 bibliographic citations, Receptor-Based Drug Design is a practical resource for pharmacologists, pharmacists, and pharmaceutical scientists; organic and medicinal chemists and biochemists; molecular biologists; biomedical researchers; and upper-level undergraduate and graduate students in these disciplines.

    • "Sinopsis" puede pertenecer a otra edición de este libro.

    Acerca del autor

    Leff Paul

    "Sobre este título" puede pertenecer a otra edición de este libro.

    Editorial
    CRC Press
    Año de publicación
    2019
    Idioma
    Inglés
    ISBN 10 
    0367400529
    ISBN 13 
    9780367400521
    Encuadernación
    Tapa blanda
    Número de edición
    1
    Número de páginas
    400
    Editor
    Leff Paul
    Contacto del fabricante
    Taylor and Francis, GPSR Taylor and Francis
    gpsr@taylorandfrancis.com

    Taylor & Francis Verlag GmbH, Kaufingerstraße 24
    München
    80331
    Alemania

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