A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery (Critical Reviews in Combinatorial Chemistry) - Tapa blanda

Chen, Taosheng

 
9780367384708: A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery (Critical Reviews in Combinatorial Chemistry)

Sinopsis



Few scientists have the multidisciplinary experience needed to control all aspects of a high-throughput screening (HTS) drug discovery project. This volume integrates the knowledge of experts in biology, chemistry, informatics, instrumentation, automation, technology development, and project management. Enabling researchers in industrial and academic settings to find the most efficient way to carry a project from start to finish, this volume identifies critical targets that are of relevance to drug discovery, discusses the components of the HTS process, and provides step-by-step instructions for an HTS project, while also examining emerging technologies and systems.



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Acerca del autor

Taosheng Chen earned a BS in biophysics and an MS in molecular cell biology from Fudan University in Shanghai, China. He received his PhD in cell and molecular biology from the University of Vermont at Burlington. Dr. Chen joined the faculty of the Department of Chemical Biology and Therapeutics and became director of the HTS Center at the St. Jude Children’s Research Hospital in Memphis in 2006. His laboratory focuses on studying the regulation of transcription factors and their implications in drug metabolism and drug resistance as well as in pediatric cancers. Dr. Chen has authored more than 20 peer-reviewed articles in the areas of cancer biology, drug metabolism, signal transduction, and drug discovery technology.

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9781420070507: A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery (Critical Reviews in Combinatorial Chemistry)

Edición Destacada

ISBN 10:  1420070509 ISBN 13:  9781420070507
Editorial: CRC Press, 2009
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