Master Control Genes in Development and Evolution: The Homeobox Story (The Terry Lectures) - Tapa dura

Gehring, Walter J.

 
9780300074093: Master Control Genes in Development and Evolution: The Homeobox Story (The Terry Lectures)
Tapa dura
ISBN 10: 0300074093 ISBN 13: 9780300074093
Editorial: Yale University Press, 1998

Sinopsis

In this fascinating book, one of the world’s most eminent developmental biologists discusses some of the exciting new insights into how genes control development. Walter Gehring describes in vivid detail his essential contributions to the landmark discovery of the homeobox, a characteristic DNA segment found in the genes of all higher organisms from the fruitfly to humans, and he explains how this has provided the key to our modern understanding of development and evolution. The book thus becomes not only a lucid discussion of genetics but also an engaging description of the art of scientific investigation.

Gehring begins his story by looking at the work of the many researchers who laid the foundation for the fields of molecular, cellular, and developmental biology, providing insightful vignettes of past and present investigators. He then describes his laboratory’s hunt for the gene that caused odd mutations in the fruitfly―in which, for example, antennae on the head were transformed into legs. He explains that researchers eventually found that the same master control genes that dictate the body plan in flies also pattern human bodies, limbs, hands, heart, and brain. And he illustrates the universality of the genetic control of development by describing the development of the eye; eyes as different as those of humans, squids, and flies, he shows, develop under the same master control gene.

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Acerca del autor

Walter J. Gehring is professor in the department of cell biology at the University of Basel, Switzerland. He recently shared the March of Dimes Prize for research in developmental biology.

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Editorial
Yale University Press
Año de publicación
1998
Idioma
Inglés
ISBN 10 
0300074093
ISBN 13 
9780300074093
Encuadernación
Tapa dura
Número de páginas
254
Contacto del fabricante
no disponible
Persona responsable
no disponible