Yuste, Rafael Dendritic Spines

ISBN 13: 9780262013505

Dendritic Spines

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9780262013505: Dendritic Spines
Reseña del editor:

Most neurons in the brain are covered by dendritic spines, small protrusions that arise from dendrites, covering them like leaves on a tree. But a hundred and twenty years after spines were first described by Ramon y Cajal, their function is still unclear. Dozens of different functions have been proposed, from Cajal's idea that they enhance neuronal interconnectivity to hypotheses that spines serve as plasticity machines, neuroprotective devices, or even digital logic elements. In Dendritic Spines, leading neurobiologist Rafael Yuste attempts to solve the "spine problem," searching for the fundamental function of spines. He does this by examining many aspects of spine biology that have fascinated him over the years, including their structure, development, motility, plasticity, biophysical properties, and calcium compartmentalization. Yuste argues that we may never understand how the brain works without understanding the specific function of spines. In this book, he offers a synthesis of the information that has been gathered on spines (much of which comes from his own studies of the mammalian cortex), linking their function with the computational logic of the neuronal circuits that use them. He argues that once viewed from the circuit perspective, all the pieces of the spine puzzle fit together nicely into a single, overarching function. Yuste connects these two topics, integrating current knowledge of spines with that of key features of the circuits in which they operate. He concludes with a speculative chapter on the computational function of spines, searching for the ultimate logic of their existence in the brain and offering a proposal that is sure to stimulate discussions and drive future research.

Biografía del autor:

Rafael Yuste is Professor in the Departments of Biological Sciences and Neuroscience at Columbia University, where he is HHMI Investigator and Codirector of the Kavli Institute for Brain Circuits.

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Rafael Yuste
Editorial: MIT Press (2010)
ISBN 10: 0262013509 ISBN 13: 9780262013505
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Rafael Yuste
Editorial: MIT Press Ltd, United States (2010)
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Descripción MIT Press Ltd, United States, 2010. Hardback. Estado de conservación: New. 237 x 182 mm. Language: English . Brand New Book. Most neurons in the brain are covered by dendritic spines, small protrusions that arise from dendrites, covering them like leaves on a tree. But a hundred and twenty years after spines were first described by Ramon y Cajal, their function is still unclear. Dozens of different functions have been proposed, from Cajal s idea that they enhance neuronal interconnectivity to hypotheses that spines serve as plasticity machines, neuroprotective devices, or even digital logic elements. In Dendritic Spines, leading neurobiologist Rafael Yuste attempts to solve the spine problem, searching for the fundamental function of spines. He does this by examining many aspects of spine biology that have fascinated him over the years, including their structure, development, motility, plasticity, biophysical properties, and calcium compartmentalization. Yuste argues that we may never understand how the brain works without understanding the specific function of spines. In this book, he offers a synthesis of the information that has been gathered on spines (much of which comes from his own studies of the mammalian cortex), linking their function with the computational logic of the neuronal circuits that use them. He argues that once viewed from the circuit perspective, all the pieces of the spine puzzle fit together nicely into a single, overarching function. Yuste connects these two topics, integrating current knowledge of spines with that of key features of the circuits in which they operate. He concludes with a speculative chapter on the computational function of spines, searching for the ultimate logic of their existence in the brain and offering a proposal that is sure to stimulate discussions and drive future research. Nº de ref. de la librería AAH9780262013505

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Rafael Yuste
Editorial: MIT Press Ltd, United States (2010)
ISBN 10: 0262013509 ISBN 13: 9780262013505
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Descripción MIT Press Ltd, United States, 2010. Hardback. Estado de conservación: New. 237 x 182 mm. Language: English . Brand New Book. Most neurons in the brain are covered by dendritic spines, small protrusions that arise from dendrites, covering them like leaves on a tree. But a hundred and twenty years after spines were first described by Ramon y Cajal, their function is still unclear. Dozens of different functions have been proposed, from Cajal s idea that they enhance neuronal interconnectivity to hypotheses that spines serve as plasticity machines, neuroprotective devices, or even digital logic elements. In Dendritic Spines, leading neurobiologist Rafael Yuste attempts to solve the spine problem, searching for the fundamental function of spines. He does this by examining many aspects of spine biology that have fascinated him over the years, including their structure, development, motility, plasticity, biophysical properties, and calcium compartmentalization. Yuste argues that we may never understand how the brain works without understanding the specific function of spines. In this book, he offers a synthesis of the information that has been gathered on spines (much of which comes from his own studies of the mammalian cortex), linking their function with the computational logic of the neuronal circuits that use them. He argues that once viewed from the circuit perspective, all the pieces of the spine puzzle fit together nicely into a single, overarching function. Yuste connects these two topics, integrating current knowledge of spines with that of key features of the circuits in which they operate. He concludes with a speculative chapter on the computational function of spines, searching for the ultimate logic of their existence in the brain and offering a proposal that is sure to stimulate discussions and drive future research. Nº de ref. de la librería AAH9780262013505

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Descripción MIT Press. Estado de conservación: New. Brand New. Nº de ref. de la librería 0262013509

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Descripción The MIT Press, 2010. Hardcover. Estado de conservación: New. 1. Nº de ref. de la librería DADAX0262013509

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Descripción 2010. Hardback. Estado de conservación: NEW. 9780262013505 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Nº de ref. de la librería HTANDREE01157045

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Descripción 2009. Hardcover. Estado de conservación: New. 178mm x 20mm x 231mm. Hardcover. biology, including structure, development, motility, and plasticity. A leading neurobiologist explores the fundamental function of dendritic spines in neural circuits by analyzing differen.Shipping may be from multiple locations in the US or from the UK, depending on stock availability. 264 pages. 0.680. Nº de ref. de la librería 9780262013505

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