For those who need persuading that dendrites are at the core of brain science, this new edition provides definitive evidence. Of special interest are the new methodologies, many introduced by the editors and their co-authors, that show in increasingly exquisite detail how the branching structures of dendrites and spines provide a rich substrate for biochemical, functional, and computational compartments. A major theme is how these compartments play essential roles in sensory processing, learning and memory. Brain scientists take note: dendrites drive the circuits that drive behavior. ( Gordon M. Shepherd, Professor of Neuroscience, Yale University School of Medicine, USA)From the Publisher:
Dendrites form the major receiving part of neurons. It is within these highly complex, branching structures that the real work of the nervous system takes place. The dendrites of neurons receive thousands of synaptic inputs from other neurons. However, dendrites do more than simply collect and funnel these signals to the soma and axon; they shape and integrate the inputs in complex ways. Despite being discovered over a century ago, dendrites received little research attention until the early 1950s. Over the past few years there has been a dramatic explosion of interest in the function of these beautiful structures. Recent new research has developed our understanding of the properties of dendrites, and their role in neuronal function.
The first edition of Dendrites was a landmark in the literature, stimulating and guiding further research. The new edition substantially updates the earlier volume, and includes 5 new chapters and colour illustrations. Its gathers new information on dendrites into a single volume, with contributions written by leading researchers in the field. It presents a survey of the current state of our knowledge of dendrites, from their morphology and development through to their electrical, chemical, and computational properties. As such it will not only be of interest to researchers and graduate-level students in neuroscience, but will also be useful to researchers in computer science and IT, psychology, physiology, and biophysics.
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Descripción Oxford University Press, 2007. Hardcover. Estado de conservación: New. Nº de ref. de la librería P110198566565
Descripción Oxford University Press, 2007. Estado de conservación: New. Brand New, Unread Copy in Perfect Condition. A+ Customer Service! Summary: 1. John C Fiala, Josef Spacek and Kristen M Harris: Dendrite structure2. Gayle M Wittenberg and Samuel S-H Wang: Evolution and scaling of dendrites3. Hollis T Cline, Jorge Santos da Silva and Jennifer Bestman: Dendrite development4. Franck Polleux and Anirvan Ghosh: Molecular determinants of dendrite and spine development5. Lindy Barrett and James Eberwine: RNA targeting, trafficking and translation in dendrites: contribution to synaptic tagging and plasticity6. Dane Chetkovich and Roger Nicoll: Organization and regulation of the post-synaptic density7. Zoltan Nusser: Subcellular distribution of neurotransmitter receptors and voltage-gated ion channels8. R Angus Silver and Mark Farrant: Neurotransmitter-gated ion channels in dendrites9. Jeffrey C Magee: Dendritic voltage-gated ion channels10. Fritjof Helmchen: Biochemical compartmentalization in dendrites11. Bernardo Sabatini and Adam Carter: Spine calcium signaling12. Wilfrid Rall: An historical perspective on modeling dendrites13. Ithai Rabinowitch, Michael London and Idan Segev: A theoretical view of the neuron as an input-output plastic device14. Nelson Spruston, Greg Stuart and Michael Hausser: Dendritic integration15. Troy Margrie and Nathan Urban: Dendrites as transmitters16. Bartlett W Mel: Why have dendrites? A computational perspective17. Gilles Laurent and Alexander Borst: Short stories about small brains: linking biophysics to computation18. Zachary F Mainen and Larry Abbott: Functional plasticity at dendritic synapses19. Anna Dunaevsky and Catherine S Woolley: Structural plasticity of dendrites20. Christophe Bernard, Mala Shah and Daniel Johnston: Dendrites and disease21. Michael Hausser, Nelson Spruston and Greg Stuart: Conclusion: the future of dendrites. Nº de ref. de la librería ABE_book_new_0198566565