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This compact book provides an excellent introduction to molecular techniques and their application to animal disease and production. I felt that this book was self contained, with everything needed for one to understand the concepts. The interested reader is, however, given ample references for further reading. This book clearly illustrates how molecular biology impinges on modern veterinary medicine and practice, and provides a useful bridge between the two fields of veterinary science and molecular biology. (David W. Burt, TIG, August 1996, Vol. 12 No. 8)
In his book Veterinary Genetics, published in 1987, I believe Frank Nicholas did an excellent service in producing a text which covered comprehensively the basic genetics and its application to the health and the breeding of animals. This new, shorter, edition is at a simpler level and concentrates rather more closely on the genetics of disease ... brings in the considerable new knowledge on specific diseases and on use of markers. I suspect it is more suitable than its predecessor both for the undergraduate vet and agriculture student and for the professional or amateur reader concerned with animal genetics and breeding ... undoubtedly a nice piece of work. Whilst the basic theory and the animal breeding applications can be found elsewhere, the content on the genetics of animal disease is, I believe, uniquely available here. (William G. Hill, University of Edinburgh, Genetical Research, 1996)
most excellent book ... It is a most comprehensive, and comprehensible, primer on genetics. It is right up to date, accurate, and clear, and it is a delight for a human geneticist to read because it is so interesting. The book is highly recommended both for its genetics (veterinarians will be well instructed by it) and for the horizons which it broadens for human geneticists. (Mary J. Seller, Journal of Medical Genetics, Vol. 33, No. 10, Oct 1996)
This book provides an introductory and up-to-date overview of those aspects of genetics that are relevant to animal disease and animal production ... it provides an excellent introduction to anyone interested in acquiring a basic understanding of genetics. Examples are drawn from the field of veterinary science and a clear account is provided of the importance of molecular biology to genetics. The various concepts are clearly and concisely expressed. (Colin Hetherington, Laboratory Animals, 30, 1996)
The writing is generally clear, realistic and quite positive on many aspects, so that many students should be tempted to get more involved in genetics. Further reading is proposed after each chapter and covers quite well the different research fields as well as most of the domestic species. The author should be congratulated for this quite comprehensive overview. (M. Tixier-Boichard, Genet Sel Evol (1997) 29)
The rather modest title to this book conceals an undertaking of heroic proportions; to introduce and summarise the whole of host genetics and current genetic methodology. (Avian Pathology, June 1997)
A clear understanding of genetics is fundamental to learning about animal disease and improvement. In this introductory, up to date, overview of the subject, a general introduction to basic genetics and molecular genetics is followed by chapters on single-gene disorders, chromosomal aberrations, immunogenetics, pharmacogenetics, parasites and pathogens, and control of inherited disorders. The final chapters cover inbreeding and conservation biology, quantitative variation and heritability, breed structure, selection, crossing, and the implications of biotechnology. The book capitalizes on the explosion of knowledge in molecular genetics, showing how this knowledge is creating a revolution in gene mapping, in the diagnosis and control of inherited diseases, and in the identification of genes.
A feature of the book is a list of single-gene disorders in domestic animals, including the molecular basis of all disorders for which the causal mutation has been determined at the DNA level. There are also lists of multifactorial disorders and chromosomal aberrations. Since knowledge about inherited disorders is continually expanding, the lists are maintained in a database, which is continually updated. Readers of the book are provided with instructions for obtaining free electronic access to this database.
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