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The most thorough and informative volume on the subject printed so far. In an extremely systematic way most of the pertinent methodological questions are analysed, and thoughtful guidelines provided....A must for all medium size and larger libraries and for those actively involved in clinical trials. (Pain)
'Comprehensive as most others on the topic are not, and thorough in most respects, the book also contains a glossary, many useful summary appendices, and much practical advice. (British Medical Journal)
A good reference for many practitioners of clinical trials... This book has many tables and figures representing the actual data from previous clinical trials, which helps maintain interest for the clinical investigator... The bibliography is particularly well done and includes not only the extensive documentation for the text, but also classic statistical papers... This book would serve as a good reference for anyone engaged in designing, implementing, or conducting a clinical trial. (Journal of the American Medical Association)
Covers with great thoroughness the design, execution, and reporting of multicenter and single-center uncrossed trials that have a clinical event as endpoint....Both the authors and the publisher are to be congratulated on the skill with which this complex book was put together...Will be the standard for instruction in and evaluation of controlled clinical trials for years to come. (The Lancet)
Scarcely any aspect of the design, organization and analysis of clinical trials is neglected....However, the presentation of the material allows it to be a book both for beginners and for readers already familiar with clinical trials. I believe it would be better to buy Dr. Meinert's book than to acquire an elementary test on clinical trials with the hope of filling the gaps from the literature. (Canadian Journal of Public Health)
[The] checklists and examples provide excellent guidance, and the text would be a valuable resource in the library of even the most experienced clinical investigators. (European Organization for Research and Treatment of Cancer)
A large amount of practical information on the design, conduct and analysis of both single centre and multi-centre trials is contained in this volume. (Short Book Reviews)
Clearly and logically presents material on each stage of a clinical trial, which should be of interest both to practitioners and to a wider statistical audience. (Royal Statistical Society)
This book is a practical manual which would be very useful for anyone about to create a clinical trials office...Recommended to specialist clinical trial centres. (Human Psychopharmacology)
This book can be safely recommended for people with a keen interest in randomized clinical trials, with an emphasis on parallel groups. I will to use it with pleasure in my work with research and teaching. (Journal of the Norwegian Medical Association, March 2013)
Reseña del editor
First published in 1986, this landmark text is the definitive guide to clinical trials, written by one of the leading experts in the field. This fully-updated second edition continues to be the most authoritative reference text on randomized clinical trials. It contains a wealth of practical information on the design, conduct, and analysis of both single center and multicenter trials. No other book on clinical trials offers as much detail on such issues as sample size calculation, stratification and randomization, data systems design, development of consent forms, publication policies, preparation of funding requests, and reporting procedures.
While the basics of design, conduct, and analysis of clinical trials remain the same, there have been significant changes since the first edition of Clinical Trials was published two decades ago. In this new edition, the author discusses the refinements and improvements made to methods and procedures, changes in the policies and guidelines underlying trials, as well as requirements for registration of trials. He also discusses current practices for data sharing, for gender representation, for treatment effects monitoring, and for ethical standards of clinical trials. The importance of the randomized controlled trial has grown significantly over time and they are now the cornerstone of all evidence-based medicine. Still rich in tables, checklists, charts, and other resources for the trialist, the second edition of Clinical Trials is an indispensable reference for clinicians, biostaticians, epidemiologists, and anyone involved in the design and implementation of a clinical trial.
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- EditorialOUP USA
- Año de publicación2012
- ISBN 10 0195387880
- ISBN 13 9780195387889
- EncuadernaciónTapa dura
- IdiomaInglés
- Número de edición2
- Número de páginas720
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ClinicalTrials: Design, Conduct and Analysis (Monographs in Epidemiology and Biostatistics)
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Hardcover. Condición: new. Hardcover. First published in 1986, this landmark text is the definitive guide to clinical trials, written by one of the leading experts in the field. This fully-updated second edition continues to be the most authoritative reference text on randomized clinical trials. It contains a wealth of practical information on the design, conduct, and analysis of both single center and multicenter trials. No other book on clinical trials offers as much detail on such issues as samplesize calculation, stratification and randomization, data systems design, development of consent forms, publication policies, preparation of funding requests, and reportingprocedures.While the basics of design, conduct, and analysis of clinical trials remain the same, there have been significant changes since the first edition of Clinical Trials was published two decades ago. In this new edition, the author discusses the refinements and improvements made to methods and procedures, changes in the policies and guidelines underlying trials, as well as requirements for registration of trials. He also discusses current practices for datasharing, for gender representation, for treatment effects monitoring, and for ethical standards of clinical trials. The importance of the randomized controlled trial has grown significantly over time and theyare now the cornerstone of all evidence-based medicine. Still rich in tables, checklists, charts, and other resources for the trialist, the second edition of Clinical Trials is an indispensable reference for clinicians, biostaticians, epidemiologists, and anyone involved in the design and implementation of a clinical trial. The classic, definitive guide to the design, conduct, and analysis of randomized clinical trials. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Nº de ref. del artículo: 9780195387889
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