This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. Examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. Although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. It strikes a good balance between epidemiologic study designs and statistical methods of data analysis.
"Sinopsis" puede pertenecer a otra edición de este libro.
Duncan C Thomas, Ph.D., is Professor of Preventive Medicine, Director of the Biostatistics Division, and Verna R Richter Chair in Cancer Research at the University of Southern California Keck School of Medicine. His primary research interest has been in the development of statistical methods for cancer epidemiology, but he also has wide-ranging interest in both environmental and genetic epidemiology. Dr Thomas also chairs organizing committees for the Genetic Analysis Workshop and the Informatics Consortium for the NCI Cooperative Family Registries for Breast and Colorectal Cancer, and he is a past President of the International Genetic Epidemiology Society.
"Sobre este título" puede pertenecer a otra edición de este libro.
EUR 3,40 gastos de envío en Estados Unidos de America
Destinos, gastos y plazos de envíoGRATIS gastos de envío en Estados Unidos de America
Destinos, gastos y plazos de envíoLibrería: Seattle Goodwill, Seattle, WA, Estados Unidos de America
hardcover. Condición: Good. Nº de ref. del artículo: mon0000020488
Cantidad disponible: 1 disponibles
Librería: ThriftBooks-Atlanta, AUSTELL, GA, Estados Unidos de America
Hardcover. Condición: Good. No Jacket. Former library book; Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less 1.74. Nº de ref. del artículo: G019515939XI3N10
Cantidad disponible: 1 disponibles
Librería: ThriftBooks-Atlanta, AUSTELL, GA, Estados Unidos de America
Hardcover. Condición: Very Good. No Jacket. Former library book; May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less 1.74. Nº de ref. del artículo: G019515939XI4N10
Cantidad disponible: 1 disponibles
Librería: ThriftBooks-Atlanta, AUSTELL, GA, Estados Unidos de America
Hardcover. Condición: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less 1.74. Nº de ref. del artículo: G019515939XI3N00
Cantidad disponible: 1 disponibles
Librería: SecondSale, Montgomery, IL, Estados Unidos de America
Condición: Very Good. Item in very good condition! Textbooks may not include supplemental items i.e. CDs, access codes etc. Nº de ref. del artículo: 00088873983
Cantidad disponible: 1 disponibles
Librería: Better World Books, Mishawaka, IN, Estados Unidos de America
Condición: Good. Used book that is in clean, average condition without any missing pages. Nº de ref. del artículo: 7934443-6
Cantidad disponible: 1 disponibles
Librería: Better World Books, Mishawaka, IN, Estados Unidos de America
Condición: Very Good. Former library book; may include library markings. Used book that is in excellent condition. May show signs of wear or have minor defects. Nº de ref. del artículo: GRP92270559
Cantidad disponible: 1 disponibles
Librería: One Planet Books, Columbia, MO, Estados Unidos de America
hardcover. Condición: Good. 1st Edition. Ships in a BOX from Central Missouri! May not include working access code. Will not include dust jacket. Has used sticker(s) and some writing and/or highlighting. UPS shipping for most packages, (Priority Mail for AK/HI/APO/PO Boxes). Nº de ref. del artículo: 000748895U
Cantidad disponible: 1 disponibles
Librería: WorldofBooks, Goring-By-Sea, WS, Reino Unido
Hardback. Condición: Very Good. The book has been read, but is in excellent condition. Pages are intact and not marred by notes or highlighting. The spine remains undamaged. Nº de ref. del artículo: GOR009011259
Cantidad disponible: 1 disponibles
Librería: Textbooks_Source, Columbia, MO, Estados Unidos de America
hardcover. Condición: Good. 1st Edition. Ships in a BOX from Central Missouri! May not include working access code. Will not include dust jacket. Has used sticker(s) and some writing or highlighting. UPS shipping for most packages, (Priority Mail for AK/HI/APO/PO Boxes). Nº de ref. del artículo: 000748895U
Cantidad disponible: 1 disponibles