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Andrea Rita Horvath’s key research interests include evidence-based laboratory medicine (EBLM) including evidence-based monitoring, guideline development, and evaluation of new biomarkers and overdiagnosis. She holds advisory roles on test utilization and reimbursement policy at the National Prescribing Service of Australia and Medicare. She has published 160 research papers and 16 book chapters and has been an invited speaker at over 100 international conferences. Her national and international leadership positions include Chair of the IFCC Committee on EBLM (2003-2008); European Communities Confederation of Clinical Chemistry and Laboratory Medicine (EC4) Secretary (2005-2007); President of the Hungarian Society (2005-2008) and the Hungarian College of Laboratory Medicine (2008-2009); President-Elect (2007-2009), President (2009-2011) and Past President (2012-2013) of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM); chair of the EFLM working group on Test Evaluation (2011-2015) and member of the Board of Directors of the American Association of Clinical Chemistry (2014-2016).

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Principles and Applications of Molecular Diagnostics - A Derivative of the Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 6th ed.

An accessible guide for clinical chemists and biologists applying molecular technology to clinical diagnosis, derived from the sixth edition of the bestselling Tietz Textbook of Clinical Chemistry and Molecular Diagnostics.

Professor of Pathology, Harvard Medical School, Cambridge, MA USA

Director of Clinical Chemistry, Boston Children's Hospital, Boston, MA USA

Professor, School of Medical Sciences, University of New South Wales, Sydney, Australia

Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT USA

Derived from the sixth edition of the bestselling Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, editors Nader Rifai, A. Rita Horvath, and Carl T. Wittwer bring you Principles and Applications of Molecular Diagnostics. This is an accessible guide for clinical chemists and biologists applying molecular technology to clinical diagnosis. The book consists of two parts: part one covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and techniques, circulating tumor cells and DNA and cellular DNA; and part two presents clinical applications of molecular diagnostics in solid tumors, prenatal diagnosis, infectious disease, genetic disease, hematopoietic malignancies, pharmacogenetics, and identity testing. For those who need a thorough yet succinct guide to using this technology for molecular testing, there is no better source.

• Explains the principles and tools of molecular biology as well as the modern analytical tools that can be used to obtain the best results
• Offers authoritative information written and edited by the top experts in molecular diagnostics
• Provides references to seminal books, review articles, and technical articles that go into greater depth, serving as a basis for further study