Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches.
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Dr. Michel Tibayrenc has worked on the evolution of infectious diseases for more than 45 years. He is a director of research emeritus at the French Institut de Recherche pour le Developpement (IRD) and the founder and editor-in-chief emeritus of the Elsevier journal Infection, Genetics and Evolution. From 1996-2021 he was the founder and principal organizer of Elsevier’s international MEEGID congress (Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases). He has held professional appointments in France, Algeria, French Guiana, Bolivia, Thailand, and the United States; is the cofounder of the Bolivian Society of Human Genetics; and is a fellow of the American Association for the Advancement of Science.
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