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Sigma Receptors (Volume 12) (Neuroscience Perspectives, Volume 12) - Tapa dura

 
9780123763501: Sigma Receptors (Volume 12) (Neuroscience Perspectives, Volume 12)
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ISBN 10: 0123763509 ISBN 13: 9780123763501
Editorial: Academic Press Inc, 1994

Sinopsis

This is the 12th in the Neuroscience Perspectives Series. The existence of sigma receptors in the central nervous system has only relatively recently been established. In line with the aims of Neuroscience Perspectives, this volume will cover the historical background of the subject, together with the physiological, molecular biological and pharmacological aspects, with a discussion on the concept of sigma receptors subtypes and their postulated relevance for CNS disorders.

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Acerca del autor

Professor Peter Jenner is a specialist in preclinical aspects of neurodegenerative diseases, notably Parkinson’s disease. He has spent the major part of his career at King’s College London where he was Head of Pharmacology for 14 years before returning to his research roots and subsequently becoming Emeritus Professor of Pharmacology. Peter has expertise in drug metabolism and pharmacokinetics but neuropharmacology based on functional models of neurodegenerative diseases has formed the major focus of his work. Peter holds a BPharm, PhD and DSc degree from the University of London. He has published well over 1000 articles with more than 700 peer reviewed papers. He is a Fellow of the Royal Pharmaceutical Society, the British Pharmacological Society, the Royal Society of Medicine and of King’s College London. Peter was recently honoured with a Doctor Honoris Causa degree from Carol Davila University of Medicine and Pharmacy, Bucharest and made an Honorary Fellow of The British Pharmacological Society for his contribution to research in to movement disorders.

Peter has worked closely with the pharmaceutical industry for many years and acts as an adviser and consultant to both major pharma and biotech companies. He has a wide knowledge of the drug discovery and drug development process and has been involved from molecule synthesis through to drug registration for use in man. Peter was the Founder, Director and Chief Scientific Officer of Proximagen, a biotech focussed on the treatment and cure of neurodegenerative diseases that was listed on AIMs and subsequently purchased by a US based healthcare company. He is a regular speaker at international meetings and also takes time to speak at Parkinson’s disease patient-carer groups across the UK.

De la contraportada

Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences.
Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas.
The sigma receptor was originally thought to be a subset of the opioid receptor family, and it is less than 10 years since it was recognized that this receptor represents unique binding sites in mammalian brain and peripheral organs, distinct from any other known neurotransmitter receptor. Since the sigma receptors exhibit high affinity for members of diverse classes of psychotropic drugs, and have been postulated to be involved in various central nervous disorders, neuroscientists have demonstrated a great deal of interest in the elucidation of these receptor sites and their biological relevance. Relatively little is known about the precise role of sigma receptors in normal brain function and in CNS disorders, despite an overwhelming research effort. This research has resulted in many controversies, some of which have been reconciled while others have not. This volume aims to update the reader on the current situation, and deals with the potential functional significance of these receptors in the brain and peripheral organs and, where appropriate, makes reference to the clinical potential of these sites.

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Editorial
Academic Press Inc
Año de publicación
1994
Idioma
Inglés
ISBN 10 
0123763509
ISBN 13 
9780123763501
Encuadernación
Tapa dura
Número de páginas
360
Editor
Itzhak Yossef
Contacto del fabricante
no disponible
Persona responsable
Barbara Criscuolo
b.criscuolo@lswr.it

Via Spadolini, 7
Milano
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Italia