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GTPases Regulating Membrane Dynamics (Volume 404) (Methods in Enzymology, Volume 404) - Tapa dura

 
9780121828097: GTPases Regulating Membrane Dynamics (Volume 404) (Methods in Enzymology, Volume 404)
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ISBN 10: 0121828093 ISBN 13: 9780121828097
Editorial: Academic Press Inc, 2005

Sinopsis

GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and effectors. Methodologies focused on biochemical, molecular and advanced imaging techniques provide a wealth of investigational tools for those currently in the field and those entering the field. Many of the methodologies are generally applicable to study of these GTPases in vitro and in vivo to elucidate function in regulation of cell proliferation and signaling in normal tissue and in disease.

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Reseña del editor

GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and effectors. Methodologies focused on biochemical, molecular and advanced imaging techniques provide a wealth of investigational tools for those currently in the field and those entering the field. Many of the methodologies are generally applicable to study of these GTPases in vitro and in vivo to elucidate function in regulation of cell proliferation and signaling in normal tissue and in disease.

*Comprehensive collection of GTPases (ARF, Sar1, Dynamin) GTPases involved in vesicle coat assembly and membrane fission
*Identification and characterization of GTPase GEFs, GAPs and effectors
*General methodologies to study GTPase function in vitro and in vivo

"Sobre este título" puede pertenecer a otra edición de este libro.

Editorial
Academic Press Inc
Año de publicación
2005
Idioma
Inglés
ISBN 10 
0121828093
ISBN 13 
9780121828097
Encuadernación
Tapa dura
Número de páginas
736
Editor
Balch W. E., Der Channing J., Hall Alan
Contacto del fabricante
no disponible
Persona responsable
Yeepin GmbH
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