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9780121550899: Understanding DNA: The Molecule and How it Works

Sinopsis

The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth. The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication. Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA.

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Acerca de los autores

Chris Calladine is Professor of Structural Mechanics at the University of Cambridge. In addition to researching aspects of structural engineering, he has applied the methods of structural mechanics to the study of flagella and DNA.

Horace Drew solved several of the first DNA crystal X-ray structures with Richard Dickerson at Caltech, and subsequently spent five years researching DNA and chromosome structures with Aaron Klug at the MRC Laboratory of Molecular Biology in Cambridge, UK He now lives in Australia and is a Principle Research Scientist at the CSIRO Division of Biomolecular Engineering in Sydney.

Ben Luisi works in the Department of Biochemistry at the University of Cambridge, where he has an appointment as professor of structural biology. He and his colleagues study the structure and mechanism of efflux pumps and the riboregulatory machinery that help to control the expression of the pumps and other complex systems in bacteria.

De la contraportada

We see DNA structures so often that it is frequently taken for granted that the molecule should not be anything but an aesthetically spiraling helix. But why should it assume such a nice structure?

The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth.

The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication.


* describes the basic units of DNA and how these form the double helix
* characterizes the various types of DNA double helix that have been found
* explains how and why DNA twists and curves
* discusses the mechanisms of DNA supercoiling
* summarizes the assembly of DNA and protein into chromosomes
* describes the latest work on protein-DNA complexes
* outlines the methods used to study DNA structure
* summarizes recent studies of DNA in disease and medicine
* explains mechanisms of non-classical inheritance
* contains over 130 illustrations, some in full colour
* contains simple exercises and further reading at the end of chapters

Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA.

From reviews of the first edition

Stylish beautifully crafted, with a logical step-by-step approach to the subject. A book from which the advanced undergraduate will benefit, and which will also generate a refreshing perspective for experts - NATURE

Authorative and lucid - SIR AARON KLUG|We see DNA structures so often that it is frequently taken for granted that the molecule should not be anything but an aesthetically spiraling helix. But why should it assume such a nice structure?

The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth.

The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication.


* describes the basic units of DNA and how these form the double helix
* characterizes the various types of DNA double helix that have been found
* explains how and why DNA twists and curves
* discusses the mechanisms of DNA supercoiling
* summarizes the assembly of DNA and protein into chromosomes
* describes the latest work on protein-DNA complexes
* outlines the methods used to study DNA structure
* summarizes recent studies of DNA in disease and medicine
* explains mechanisms of non-classical inheritance
* contains over 130 illustrations, some in full colour
* contains simple exercises and further reading at the end of chapters

Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA.

From reviews of the first edition

Stylish beautifully crafted, with a logical step-by-step approach to the subject. A book from which the advanced undergraduate will benefit, and which will also generate a refreshing perspective for experts - NATURE

Authorative and lucid - SIR AARON KLUG

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Travers, Andrew
Publicado por Academic Press, 2004
ISBN 10: 0121550893 ISBN 13: 9780121550899
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Travers Andrew Luisi Ben Drew Horace Calladine Chris R.
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Calladine, Chris R.
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Condición: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study copy. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,950grams, ISBN:9780121550899. Nº de ref. del artículo: 5570828

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Andrew Travers Ben Luisi Horace Drew Chris R. Calladine
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Calladine, Chris R.
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Condición: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,950grams, ISBN:9780121550899. Nº de ref. del artículo: 9789606

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Travers Andrew Luisi Ben Drew Horace Calladine Chris R.
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Calladine, Chris R.; Drew, Horace; Luisi, Ben; Travers, Andrew
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Hardcover. Condición: Good. 3rd Edition. Minor edge and corner wear; no dj; lightly scuffed and scratched; corners are gently bumped and rubbed; some light shelf wear; ex-library with the usual library markings; overall a nice used THIRD EDITION! Full-color pictorial boards with red and white lettering. 334 informative and educational pages nicely enhanced by black and white and full-color photographs and illustrations! "The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth. The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication. Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA." (THIRD EDITION). Nº de ref. del artículo: 052019

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Chris R. Calladine, Horace Drew, Ben Luisi, Andrew Travers
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