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Descripción Soft Cover. Condición: new. This item is printed on demand. Nº de ref. del artículo: 9783642752209
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Descripción Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Among the first diseases for which a viral etiology was esta blished were tumors, lymphomas, and sarcomas in chickens, shown by Ellermann and Bang (1908) and Rous (1910) to be transmissible with cell-free filtrates. The broad significance of these discoveries was not fully recognized at first, mainly because chickens were perceived as too distanly related to humans to provide useful and relevant models for human disease. Change came slowly. In 1936 Bittner found that a viral agent is involved in the causation of mammary cancer in mice, and in 1957 Gross discovered the first murine leukemia virus. In the years following numerous tumor-inducing viruses, infecting all classes of verte brates, were isolated. The decisive impulse for the development of the RNA tumor virus field sprang from advances in cell culture. In 1958 Temin and Rubin, following initial observations of Manaker and Groupe, worked out the conditions for virus-induced tumori genic transformation in cell culture and made this transform ation the basis for a quantitative assay of viral infectivity and oncogenicity. The genetic and cell biological studies that grew out of Rubin's and Temin's groundwork quickly brought into focus two puzzling problems: a requirement for DNA synthesis early in the lifecycle of the RNA tumor viruses, and the existence of genetic information in the virus that is needed for oncogenesis but not for virus reproduction. 280 pp. Englisch. Nº de ref. del artículo: 9783642752209
Descripción Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A synthesis of current knowledge on retrovirology, cov- ering the literature and the relevance of this rapidly advancing area to HIV and AIDS research.List of Contents.- Retrovirus Phylogeny and Evolution.- Integration of Retroviral DNA.- The Structure . Nº de ref. del artículo: 5069743
Descripción Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Among the first diseases for which a viral etiology was esta blished were tumors, lymphomas, and sarcomas in chickens, shown by Ellermann and Bang (1908) and Rous (1910) to be transmissible with cell-free filtrates. The broad significance of these discoveries was not fully recognized at first, mainly because chickens were perceived as too distanly related to humans to provide useful and relevant models for human disease. Change came slowly. In 1936 Bittner found that a viral agent is involved in the causation of mammary cancer in mice, and in 1957 Gross discovered the first murine leukemia virus. In the years following numerous tumor-inducing viruses, infecting all classes of verte brates, were isolated. The decisive impulse for the development of the RNA tumor virus field sprang from advances in cell culture. In 1958 Temin and Rubin, following initial observations of Manaker and Groupe, worked out the conditions for virus-induced tumori genic transformation in cell culture and made this transform ation the basis for a quantitative assay of viral infectivity and oncogenicity. The genetic and cell biological studies that grew out of Rubin's and Temin's groundwork quickly brought into focus two puzzling problems: a requirement for DNA synthesis early in the lifecycle of the RNA tumor viruses, and the existence of genetic information in the virus that is needed for oncogenesis but not for virus reproduction. Nº de ref. del artículo: 9783642752209
Descripción Paperback. Condición: Brand New. reprint edition. 270 pages. 9.25x6.10x0.63 inches. In Stock. Nº de ref. del artículo: x-3642752209
Descripción Condición: New. Editor(s): Swanstrom, Ronald; Vogt, Peter K. Series: Current Topics in Microbiology and Immunology. Num Pages: 270 pages, 6 black & white illustrations, 12 black & white tables, biography. BIC Classification: MJCJ; MJCM; MMFM. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 14. Weight in Grams: 428. . 2011. Softcover reprint of the original 1st ed. 1990. Paperback. . . . . Nº de ref. del artículo: V9783642752209