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Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979914ISBN 13: 9781493979912
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph presents a groundbreaking scholarly treatment of the German mathematician Jost Bürgi's original work on logarithms, Arithmetische und Geometrische Progreß Tabulen. It provides the first-ever English translation of Bürgi's text and illuminates his role in the development of the conception of logarithms, for which John Napier is traditionally given priority. High-resolution scans of each page of the his handwritten text are reproduced for the reader and as a means of preserving an important work for which there are very few surviving copies.The book begins with a brief biography of Bürgi to familiarize readers with his life and work, as well as to offer an historical context in which to explore his contributions. The second chapter then describes the extant copies of the Arithmetische und Geometrische Progreß Tabulen, with a detailed description of the copy that is the focus of this book, the 1620 'Graz manuscript'. A complete facsimile of the text is included in the next chapter, along with a corresponding transcription and an English translation; a transcription of a second version of the manuscript (the 'Gdansk manuscript') is included alongside that of the Graz edition so that readers can easily and closely examine the differences between the two. The final chapter considers two important questions about Bürgi's work, such as who was the copyist of the Graz manuscript and what the relationship is between the Graz and Gdansk versions. Appendices are also included that contain a timeline of Bürgi's life, the underlying concept of Napier's construction of logarithms, and scans of all 58 sheets of the tables from Bürgi's text.Anyone with an appreciation for the history of mathematics will find this book to be an insightful and interesting look at an important and often overlooked work. It will also be a valuable resource for undergraduates taking courses in the history of mathematics, researchers of the history of mathematics, and professors of mathematics education who wish to incorporate historical context into their teaching. 272 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979272ISBN 13: 9781493979271
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Ever since the Montgolfier's hot air balloon carried a chicken, a goat, and a duck into the Parisian skies, scientists have dreamed of contraptions to explore the atmosphere. With the advent of the space age, new airborne inventions were needed. From the Soviet Venus balloons to the advanced studies of blimps and airplanes for the atmospheres of Mars and Titan, Drifting on Alien Winds surveys the many creative and often wacky ideas for exploring alien skies. Through historical photographs and stunning original paintings by the author, readers also explore the weather on planets and moons, from the simmering acid-laden winds of Venus to liquid methane-soaked skies of Titan. 256 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979884ISBN 13: 9781493979882
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume aims to present a large panel of techniques for the study of Plant Cell Division. Plant Cell Division: Methods and Protocols captures basic experimental protocols that are commonly used to study plant cell division processes, as well as more innovative procedures. Chapters are split into five parts covering several different aspect of plant cell division such as, cell cultures for cell division studies, cell cycle progression and mitosis, imaging plant cell division, cell division and morphogenesis, and cytokinesis. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Plant Cell Division: Methods and Protocols is a valuable tool for the study of plant cell division at both the cellular and molecular levels, and in the context of plant development. 260 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979361ISBN 13: 9781493979363
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Applied Predictive Modeling covers the overall predictive modeling process, beginning with the crucial steps of data preprocessing, data splitting and foundations of model tuning. The text then provides intuitive explanations of numerous common and modern regression and classification techniques, always with an emphasis on illustrating and solving real data problems. The text illustrates all parts of the modeling process through many hands-on, real-life examples, and every chapter contains extensive R code for each step of the process.This multi-purpose text can be used as an introduction to predictive models and the overall modeling process, a practitioner's reference handbook, or as a text for advanced undergraduate or graduate level predictive modeling courses. To that end, each chapter contains problem sets to help solidify the covered concepts and uses data available in the book's R package.This text is intended for a broad audience as both an introduction to predictive models as well as a guide to applying them. Non-mathematical readers will appreciate the intuitive explanations of the techniques while an emphasis on problem-solving with real data across a wide variety of applications will aid practitioners who wish to extend their expertise. Readers should have knowledge of basic statistical ideas, such as correlation and linear regression analysis. While the text is biased against complex equations, a mathematical background is needed for advanced topics. 616 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 0387722076ISBN 13: 9780387722078
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Advanced maths students have been waiting for this, the third edition of a text that deals with one of the fundamentals of their field. This book contains a systematic treatment of probability from the ground up, starting with intuitive ideas and gradually developing more sophisticated subjects, such as random walks and the Kalman-Bucy filter. Examples are discussed in detail, and there are a large number of exercises. This third edition contains new problems and exercises, new proofs, expanded material on financial mathematics, financial engineering, and mathematical statistics, and a final chapter on the history of probability theory. 360 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493980122ISBN 13: 9781493980123
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides a practical, comprehensive overview on benign and malignant disease of the adult kidney. The text addresses the topic of assessment and management of patients with surgical renal disease. Within this scope, it includes hereditary and spontaneous renal neoplasms, as well as non-neoplastic disease that manifests as a clinically relevant mass. The book is organized into chapters focusing on discrete disease entities and incorporating pathology, surgical management, oncologic therapy, radiologic findings, and molecular alterations. This text is designed to address relevant areas of clinical management of renal neoplastic and non-neoplastic disease across multiple specialties and levels of training.Written by experts in the field, The Kidney: A Comprehensive Guide to Pathologic Diagnosis and Management is a valuable resource on the diagnosis and management of patients with not only renal cell carcinoma, but also other renal processes that require surgical intervention. 228 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979337ISBN 13: 9781493979332
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and bio targeting. The heart of the book presents oncological approaches (supportive, radiation and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons andcancer specialists alike. 384 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493980289ISBN 13: 9781493980284
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This second edition expands upon the previous volume with additional emphasis on recent innovation in basic renal research and has a more holistic approach on associated disorders such as complications associated with peritoneal dialysis, ischemic acute kidney injury, the sympathetic nervous system, and vascular calcification. The book is divided into five parts: Part I provides a number of in vitro, in vivo, and ex vivo models of kidney disease and associated complications; Part II looks at recent advances in imaging techniques; Part III covers recent developments in studying metabolism in renal ischemia and reperfusion; Part IV addresses study and measurement of vascular calcification; and Part V explores analytical techniques that are both topical and of widespread relevance to the study of experimental renal disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Kidney Research: Experimental Protocols, Second Edition is a valuable collection of protocols useful to new and experienced researchers who are interested in the field of Nephrology. 304 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493980262ISBN 13: 9781493980260
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume combines protocols that encompass the true variety of investigation done on superantigens in the fields of microbiology, immunology, molecular biology, biochemistry, and cellular biology, with a strong focus on disease models utilized to determine the role of superantigens in human disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and cutting-edge, Superantigens: Methods and Protocols contains a detailed and wide breadth of subject coverage that any scientist, clinician, or industry professional interested in this field will find valuable. 240 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979973ISBN 13: 9781493979974
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This second edition volume brings together the experiences of leading scientists in the discipline of cancer gene profiling. Because cancer genes can be profiled in many different ways, Cancer Gene Profiling: Methods and Protocols, Second Edition explores different techniques and approaches needed to understand the key stages of cancer development, as using only one technique would be insufficient. This book provides readers with an overview of the state-of-the-art methods that will enable them to perform these experiments, and demonstrates the kind of analysis that is possible in our current biomedical research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and cutting-edge, Cancer Gene Profiling: Methods and Protocols, Second Edition is a great resource for any student or practitioner with an interest in cancer gene profiling, and can be used in any well-equipped research laboratory. 268 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493980157ISBN 13: 9781493980154
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. The book begins with chapters exploring methods to detect expression levels of PTEN in normal and diseased human specimens; methods to evaluate specific PTEN function in brain cancer; methods that utilize a new biosensor to measure PTEN regulation; and techniques to measure post-transcriptional regulation of PTEN by micoRNAs and ceRNAs. Other chapters present methods describing novel techniques to detect PTEN localization and previously unstudied structural features of PTEN measured through X-Ray Crystallography and Hydrogen Deuterium Exchange Mass Spectrometry. The book concludes with methods to study PTEN function in model organisms including mice and C. elegans. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and thorough, PTEN: Methods and Protocols is a valuable collection of methodologies and protocols useful to researchers who are interested in the PTEN field. 336 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979876ISBN 13: 9781493979875
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This valuable collection aims to provide a collection of frequently used statistical methods in the field of proteomics. Although there is a large overlap between statistical methods for the different 'omics' fields, methods for analyzing data from proteomics experiments need their own specific adaptations. To satisfy that need, Statistical Analysis in Proteomics focuses on the planning of proteomics experiments, the preprocessing and analysis of the data, the integration of proteomics data with other high-throughput data, as well as some special topics. Written for the highly successful Methods in Molecular Biology series, the chapters contain the kind of detail and expert implementation advice that makes for a smooth transition to the laboratory.Practical and authoritative, Statistical Analysis in Proteomics serves as an ideal reference for statisticians involved in the planning and analysis of proteomics experiments, beginners as well as advanced researchers, and also for biologists, biochemists, and medical researchers who want to learn more about the statistical opportunities in the analysis of proteomics data. 324 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979752ISBN 13: 9781493979752
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides an understanding of the factors involved in nuclear reprogramming, which is essential for the success of reprogramming. The book is aimed at reprogramming differentiated cells and germ line transmission of pluripotent stem cells and features chapters that deal with reprogramming-related issues such as analysis of mitochondrial DNA in reprogrammed cells and the isolation of reprogramming intermediates; alternative methods for nuclear transfer; the production of germ-line chimeras from embryonic stem cells and induced pluripotent stem cells; and neonatal care and management of somatic cell nuclear transfer derived offspring. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, is the perfect guide for molecular biologists, stem cell biologists, clinicians, biotechnologists, students, veterinarians and animal care technicians involved with reprogramming, nuclear transfer and transgenesis. 284 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493980025ISBN 13: 9781493980024
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent efforts to engage more explicitly with the interpretation of emotions in archaeology have sought new approaches and terminology to encourage archaeologists to take emotions seriously. This is part of a growing awareness of the importance of senses-what we see, smell, hear, and feel-in the constitution and reconstitution of past social and cultural lives. Yet research on emotion in archaeology remains limited, despite the fact that such states underpin many studies of socio-cultural transformation. The Archaeology of Anxiety draws together papers that examine the local complexities of anxiety as well as the variable stimuli-class or factional struggle, warfare, community construction and maintenance, personal turmoil, and responsibilities to (and relationships with) the dead-that may generate emotional responses of fear, anxiousness, worry, and concern. The goal of this timely volume is to present fresh research that addresses the material dimension of rites and performances related to the mitigation and negotiation of anxiety as well as the role of material culture and landscapes in constituting and even creating periods or episodes of anxiety. 228 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493991299ISBN 13: 9781493991297
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book covers a wide range of state-of-the-art methodologies and detailed protocols currently used to study the actions that lipid-activated nuclear receptors and their co-regulators have in tissues and immune cell types considered classic metabolic 'powerhouses'. This includes the liver, adipose tissue, and monocytes/macrophages present in these and other metabolic tissues. While the main focus is on the oxysterol receptor or Liver X Receptor (LXR), the majority of the methods described can be easily applied to multiple nuclear receptors, as well as to other tissues or cell types. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Lipid-Activated Nuclear Receptors: Methods and Protocols serves as an ideal guide for researchers pursuing the vital study of nuclear receptor biology and beyond. 232 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493980459ISBN 13: 9781493980451
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book introduces the theoretical fundamentals for modeling queues in discrete-time, and the basic procedures for developing queuing models in discrete-time. There is a focus on applications in modern telecommunication systems. It presents how most queueing models in discrete-time can be set up as discrete-time Markov chains. Techniques such as matrix-analytic methods (MAM) that can used to analyze the resulting Markov chains are included. This book covers single node systems, tandem system and queueing networks. It shows how queues with time-varying parameters can be analyzed, and illustrates numerical issues associated with computations for the discrete-time queueing systems. Optimal control of queues is also covered. Applied Discrete-Time Queues targets researchers, advanced-level students and analysts in the field of telecommunication networks. It is suitable as a reference book and can also be used as a secondary text book in computer engineering and computer science. Examples and exercises are included. 408 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979949ISBN 13: 9781493979943
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This title brings to light the discoveries and insights into the lives of many marine species made possible over the last decade by passive acoustic recorders (PAR). Pop-ups, ARF, HARP, EAR, Bprobe, C-POD Atag, and Dtag are the acronyms of some of the many PARs that have changed our understanding of how marine animals live and strive in the ocean. Various types of PARs are used by different investigators in different areas of the world. These recorders have accumulated copious amounts of very important data, unveiling previously unknown information about large marine animals. Temporal, seasonal and spatial distribution patterns have been uncovered for many marine species. There have been many discoveries, new understandings and insights into how these animals live in and utilize the ocean and the importance of acoustics in their lives. Listening Within the Ocean summarizes these important discoveries, providing both a valuable resource for researchers and enjoyable reading for non-professionals interested in marine life. 424 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979655ISBN 13: 9781493979653
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. Eleven comprehensive chapters provide pathologists and researchers in various sub-disciplines of toxicology with a comprehensive review of the methods and approaches for immunohistochemical staining in various target tissues. It explores the tissue-antigen and antibody-specific problems that may be encountered during the staining procedures and provide potential avenues for resolving various methodological issues. Special attention is paid to the latest enhancement procedures for antigen retrieval and visualization as well as image analysis and antigen quantification. Written by leading researchers in toxicology and pathology, this book is a significant resource for toxicologists and pathologists working with rodents, monkeys and aquatic animal tissues. 244 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493980254ISBN 13: 9781493980253
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents an overview of contemporary quantitative proteomics methods along with instructions on data interpretation, while providing examples on how to implement proteomics into systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and practical, Proteomics in Systems Biology: Methods and Protocols is a valuable resource for researchers who are interested in using proteomics techniques to help answer biological and medical questions. 328 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979248ISBN 13: 9781493979240
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This classic text, first published in 1990, is designed to introduce law students, law teachers, practitioners, and judges to the basic ideas of mathematical probability and statistics as they have been applied in the law. The third edition includes over twenty new sections, including the addition of timely topics, like New York City police stops, exonerations in death-sentence cases, projecting airline costs, and new material on various statistical techniques such as the randomized response survey technique, rare-events meta-analysis, competing risks, and negative binomial regression. The book consists of sections of exposition followed by real-world cases and case studies in which statistical data have played a role. The reader is asked to apply the theory to the facts, to calculate results (a hand calculator is sufficient), and to explore legal issues raised by quantitative findings. The authors' calculations and comments are given in the back of the book. As with previous editions, the cases and case studies reflect a broad variety of legal subjects, including antidiscrimination, mass torts, taxation, school finance, identification evidence, preventive detention, handwriting disputes, voting, environmental protection, antitrust, sampling for insurance audits, and the death penalty. A chapter on epidemiology was added in the second edition. In 1991, the first edition was selected by the University of Michigan Law Review as one of the important law books of the year. 692 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493980114ISBN 13: 9781493980116
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume guides readers through the field of systems medicine by defining the terminology, and describing how established computational methods form bioinformatics and systems biology can be taken forward to an integrative systems medicine approach. Chapters provide an outlook on the role that systems medicine may or should play in various medical fields, and describe different facets of the systems medicine approach in action. Ultimately it introduces tools, resources and methodologies from bioinformatics and systems biology, and how to apply these in a systems medicine project. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, and discuss experimental and computational approaches, methods, and tools that should be considered for a successful systems medicine project. Systems Medicine aims to motivate and provide guidance for collaborations across disciplines to tackle today's challenges related to human health and well-being. 492 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979825ISBN 13: 9781493979820
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents an overview of recent advances, innovative applications, and future prospects of in vitro embryogenesis in higher plants. The book's chapters are divided into five parts: Part I contains reviews on general topics (microspore; zygotic and somatic embryogenesis; in vitro and in vivo asexual embryogenesis; advances on the genetic, physiological, and proteomic knowledge of somatic embryo formation; role of apoptosis and mitochondria in somatic embryogenesis; and innovation in the use of bioreactors). The remaining four parts discuss step-wise protocols on somatic embryogenesis in selected horticultural plants (Part II); forest trees (Part III); gametic embryogenesis (Part IV); and pivotal topics, such as the detection of epigenetics modifications during microspore embryogenesis, the in vitro embryogenesis and plant regenerations from isolated zygotes, the synthetics seed production, the induction and maturation of somatic embryos, and the cryostorage of embryogenic cultures (Part V). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and thorough, In Vitro Embryogenesis in Higher Plants, is a useful source of information and ideas for plant tissue culturists, cell biologists, embryologists, horticulturists, and operators of commercial nurseries. This book will introduce the fascinating work in in vitro embryogenesis in higher plants to students and young scientists. 576 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979795ISBN 13: 9781493979790
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This third edition volume expands upon the previous editions with new research topics and numerous leading-edge HIV protocols. This book contains chapters that cover various aspects of HIV-1 replication and are helpful for investigating the mechanisms of HIV-1 replication or pathogenesis. The chapters are grouped into six sections: HIV early events; HIV-1 RNA structure and RNA-protein interactions; HIV-1 post-integration events; HIV-1 pathogenesis in animal models; tools to study HIV-1 latency; and Neuro AIDS. Chapters are written by research experts who have diligently developed techniques, improved them, simplified them, or applied them to their own HIV research. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, HIV Protocols, Third Edition is a great resource for HIV research, and contains many significant tips and tricks rarely mentioned in standard protocols. 404 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979760ISBN 13: 9781493979769
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This extensive volume explores areas of intense activity related to the very early commitment of stem cells to particular lineages and the progression of differentiation to mature cell stages. Research on embryonic stem cells continues to move very quickly, thus the kinds of studies continue to expand and diversify, and methodologies are continuously being refined and improved, which this book reflects. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions on their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and fully updated, Embryonic Stem Cell Protocols, Third Edition serves as an ideal reference for researchers investigating this rich area of study. 468 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979892ISBN 13: 9781493979899
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents protocols on yeast cytokinesis that will help Molecular and Cellular Biology researchers in the use of these microorganisms to approach the study of general or specific key questions in cytokinesis. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Yeast Cytokinesis: Methods and Protocols provides practical and step-by-step detailed protocols useful for a wide audience ranging from experienced researchers to beginners in the use of yeasts. 408 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 149397968XISBN 13: 9781493979684
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This contemporary presentation of statistical methods featuresextensive use of graphical displays for exploring data and fordisplaying the analysis. The authors demonstrate how to analyzedata-showing code, graphics, and accompanying tabular listings-forall the methods they cover. Complete R scripts for all examplesand figures are provided for readers to use as models for their ownanalyses.This book can serve as a standalone text for statistics majors at themaster's level and for other quantitatively oriented disciplines atthe doctoral level, and as a reference book for researchers. Classical concepts andtechniques are illustrated with a variety of case studies using both newer graphicaltools and traditional tabular displays.New graphical material includes:an expanded chapter on graphicsa section on graphing Likert Scale Data to build on the importance ofrating scales in fields from population studies to psychometricsa discussion on design of graphics that will work for readers withcolor-deficient visionan expanded discussion on the design of multi-panel graphicsexpanded and new sections in the discrete bivariate statistics capteron the use of mosaic plots for contingency tables including the n×2×2tables for which the Mantel-Haenszel-Cochran test is appropriatean interactive (using the shiny package) presentation of the graphicsfor the normal and t-tables that is introduced early and used in manychapters 932 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493980270ISBN 13: 9781493980277
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume discusses the latest advancements and technologies used in cancer drug resistance research. Cancer Drug Resistance: Overviews and Methods contains chapters that cover topics such as: studying the mechanics of resistance to DNA damaging therapeutic drugs; studies to delineate the role of efflux transporters; expression of drug transporters; resistance to targeted therapies in breast cancer; the role of microRNAs in current pancreatic cancer treatment; and cancer exosomes as mediators of drug resistance or clinical and molecular methods in drug development and the use of bioinformatics in the management of cancer drug resistance data. Written in the highly successful Methods in Molecular Biology series format, chapters include overviews of the main issues in cancer drug resistance and the respective mechanisms, as well as introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cancer Drug Resistance: Overviews and Methods, is a valuable resource to researchers, oncobiologists and clinical oncologists or anyone else who is interested in the study of cancer and its drug resistances. 332 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493990977ISBN 13: 9781493990979
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Libro Impresión bajo demanda
Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This comprehensive update of the now classic text applies the most current findings across disciplines to the treatment of pathogenic human stress arousal. New and revised chapters bring together the art and science of intervention, based in up-to-date neuroscience, starting with an innovative model tracing the stress-to-disease continuum throughout the systems of the human body. The authors detail the spectrum of physiological and psychological treatments for the stress response, including cognitive therapy, neuromuscular relaxation, breathing exercises, nutritional interventions, and pharmacotherapy. They also assess the strengths and limitations of widely-used measures of the stress response and consider the value of personality factors, cultural considerations, and resilience in stress mediation.Included in the coverage:The anatomy and physiology of the human stress response.Advances in neuroscience: implications for stress.Crisis intervention and psychological first aid.Neurophysiological rationale for the use of the relaxation response.Physical exercise and the human stress response.The pharmacological management of stress reactions. Disaster Mental Health Planning.Cultural Awareness and Stress.The Fourth Edition of A Clinical Guide to the Treatment of Human Stress Response offers readers a dual perspective, exceedingly useful in examining the origins of the stress response, and in preventing and treating the response itself. This rich integrative volume will join its predecessors in popularity among practitioners and students across disciplines and specialties. 652 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979817ISBN 13: 9781493979813
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Libro Impresión bajo demanda
Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume aims to be a collection of essential protocols in iPS cell field.Induced Pluripotent Stem (iPS) Cells: Methods and Protocols guides readers through multiple facets of stem cell biology, lineage commitment and differentiation. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Induced Pluripotent Stem (iPS) Cells: Methods and Protocols provides protocols that can be used by both experts and novices interested in stem cells. 512 pp. Englisch.
Publicado por Springer New York Mrz 2019, 2019
ISBN 10: 1493979698ISBN 13: 9781493979691
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
Libro Impresión bajo demanda
Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This expert reference provides a broad, comprehensive review of the major domains of sexual offending. Beginning with an integrated etiological model of sexual offending, chapters follow addressing the primary predisposing conditions related to sexual offending (e.g. pedophilic, hebephilic, paraphilic rape and non-contact paraphilic disorders, hyper sexuality and personality factors). In addition, special subgroups of sexual offenders (females, youth and the intellectually disable) are considered. Both broad and specific perspectives on the assessment of sexual offenders are provided. Overviews are offered of clinical and forensic evaluations of such offenders and the utility of structured psychological assessment. A novel conceptual model of risk assessment is proposed. More specifically, each of the primary approaches or instruments related to risk assessment of sexual offending are addressed: the Static risk assessment measures, the Sex Offender Risk Appraisal Guide, structured professional judgment, and the varied measures of dynamic or criminogenic needs assessment. Finally, multiple aspects of management of sexual offenders are discussed including models of psychosocial treatment, the question of the effectiveness of such treatment, biological interventions, civil commitment, circles of support, and the containment approach to community management. Chapters are authored by both prominent experts and experienced professionals for a breadth of perspective. Among the topics covered: Pedophilic, Hebephilic, Rape Paraphilic Disorders and the variety of Non Contact sexual offending conditionsPersonality, related conditions, & their association with sexual offending: motivators and disinhibition in context.Disorders of hyper sexuality.Assessments of sexual offenders, including the role of psychological testing, clinical & interview approaches, as well as forensic evaluationsConceptual models of risk assessment & discussion of specific static, dynamic & structured clinical risk assessment approachesModels of & reviews of treatment outcome with sexual offenders, including psychotherapy, psychopharmacology and castration, the containment approach, civil commitment & circles of supportOverview of public policy issues & an evidence-based perspective on sex offender registration and residential restrictions. This breadth of material in Sexual Offenders will help practitioners gain multiple levels of clinical insight as well as giving them up-to-date practical tools and techniques for working with this problematic class of individuals. 912 pp. Englisch.