Biomimetic Modelling of Organic Synthesis: Involving Cyclodextrins: Cyclodextrins as enzyme models

Biomimetic Modelling of Organic Synthesis: Studies Involving Cyclodextrins, briefely describes about the cyclodextrins and the structural features of its exterior surface and internal cavity, and its applications in biomimetic synthesis of selenazoles, thiazoles and amino thiazoles; nucleophilic ring opening, oxidative deprotections, substitution and addition reactions in aqeous media. Cyclodextrins are mimicking enzymes in their capability to bind substrates selectively and catalyze chemical reactions through the reversible formation of host-guest complexes by non-covalent bonding. Based on this phenomena, in this work efforts have been made for attaining higher regioselectivities in various ring opening reactions. This work also explores the anionic reactions in aqeous media and in open air atmosphere and contributes greately to the green chemistry by minimising the usage of hazardous organic solvents.

Dr. Mendu Narender was born in India. He received his Ph.D. in 2008, from IICT, India, under the guidance of Dr. K. Rama Rao. Then, he joined in Prof. Uli Kazmaier's group-2008, Germany. Later he worked with Prof. Jun'ichi Uenishi as a JSPS fellow-2009. In 2012, he recieved TBRF fellowship to work with Prof. Takeo Kawabata, Kyoto University, Japan.