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The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.
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- EditorialSpringer
- Año de publicación2011
- ISBN 10 3709104386
- ISBN 13 9783709104385
- EncuadernaciónTapa dura
- Número de páginas344
- EditorThalhamer Josef, Weiss Richard, Scheiblhofer Sandra
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Gene Vaccines
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Gene Vaccines
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Gene Vaccines
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Descripción Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models.Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance.The present book gives an update of the 'world of naked gene vaccines', namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing 'burning questions'. 344 pp. Englisch. Nº de ref. del artículo: 9783709104385
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Gene Vaccines
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Descripción Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Only updated volume on gene vaccines focus on the most promisingApproaches towards gene vaccinationApproaches close to or already in clinical use objective comparison of different methods and protocolsThe induction of antigen-specif. Nº de ref. del artículo: 5249531
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Descripción Hardcover. Condición: new. Hardcover. The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models.Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance.The present book gives an update of the world of naked gene vaccines, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing burning questions. The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Nº de ref. del artículo: 9783709104385
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Descripción Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models.Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance.The present book gives an update of the 'world of naked gene vaccines', namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing 'burning questions'. Nº de ref. del artículo: 9783709104385
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Descripción Condición: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Nº de ref. del artículo: ria9783709104385_lsuk
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