Omeprazole: A comparative in vitro dissolution study of different brands of omeprazole magnesium with reference product Losec 20

 
9783659253959: Omeprazole: A comparative in vitro dissolution study of different brands of omeprazole magnesium with reference product Losec 20

The main objective of present investigation was to study the dissolution pattern of most commercially available formulations of omeprazole in Bangladesh . Omeprazole magnesium is the most common antiulcerant in Bangladesh which are widely prescribed by the physicians for peptic ulcer & GERD. Ten national brands with reference brand of Omeprazole magnesium capsules were studied in stimulated gastric medium (pH 1.2) for first 2 hours and then in simulated intestinal medium (pH 6.8) for next 45 minutes using USP reference dissolution apparatus (Type 1 ) Among most of these locally manufactured Omeprazole brands showed compatible dissolution pattern & release kinetics compared with the reference brand. It was concluded from the study that most of the formulations were equivalent and there was no intra and inter variation between each and every formulation.

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About the Author:

Mr. Jayanta Kishor Chakrabarty hailing from Comilla, Bangladesh, obtained his M.Pharm degree from Dept. of Pharmaceutical Technology, University of Dhaka. Now he is employed in Northern University Bangladesh (NUB) as a Lecturer. He is interested to build his career in reseach sector.

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1.

Kishor chakrabarty, Jayanta / Chandra Bachar, Sitesh
ISBN 10: 3659253952 ISBN 13: 9783659253959
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Descripción Estado de conservación: New. Publisher/Verlag: LAP Lambert Academic Publishing | A comparative in vitro dissolution study of different brands of omeprazole magnesium with reference product Losec 20 | The main objective of present investigation was to study the dissolution pattern of most commercially available formulations of omeprazole in Bangladesh . Omeprazole magnesium is the most common antiulcerant in Bangladesh which are widely prescribed by the physicians for peptic ulcer & GERD. Ten national brands with reference brand of Omeprazole magnesium capsules were studied in stimulated gastric medium (pH 1.2) for first 2 hours and then in simulated intestinal medium (pH 6.8) for next 45 minutes using USP reference dissolution apparatus (Type 1 ) Among most of these locally manufactured Omeprazole brands showed compatible dissolution pattern & release kinetics compared with the reference brand. It was concluded from the study that most of the formulations were equivalent and there was no intra and inter variation between each and every formulation. | Format: Paperback | Language/Sprache: english | 108 pp. Nº de ref. de la librería K9783659253959

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2.

Jayanta Kishor chakrabarty
Editorial: LAP Lambert Academic Publishing Nov 2013 (2013)
ISBN 10: 3659253952 ISBN 13: 9783659253959
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BuchWeltWeit Inh. Ludwig Meier e.K.
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Descripción LAP Lambert Academic Publishing Nov 2013, 2013. Taschenbuch. Estado de conservación: Neu. Neuware - The main objective of present investigation was to study the dissolution pattern of most commercially available formulations of omeprazole in Bangladesh . Omeprazole magnesium is the most common antiulcerant in Bangladesh which are widely prescribed by the physicians for peptic ulcer & GERD. Ten national brands with reference brand of Omeprazole magnesium capsules were studied in stimulated gastric medium (pH 1.2) for first 2 hours and then in simulated intestinal medium (pH 6.8) for next 45 minutes using USP reference dissolution apparatus (Type 1 ) Among most of these locally manufactured Omeprazole brands showed compatible dissolution pattern & release kinetics compared with the reference brand. It was concluded from the study that most of the formulations were equivalent and there was no intra and inter variation between each and every formulation. 108 pp. Englisch. Nº de ref. de la librería 9783659253959

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3.

Jayanta Kishor chakrabarty
Editorial: LAP Lambert Academic Publishing Nov 2013 (2013)
ISBN 10: 3659253952 ISBN 13: 9783659253959
Nuevos Taschenbuch Cantidad: 1
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Rheinberg-Buch
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Descripción LAP Lambert Academic Publishing Nov 2013, 2013. Taschenbuch. Estado de conservación: Neu. Neuware - The main objective of present investigation was to study the dissolution pattern of most commercially available formulations of omeprazole in Bangladesh . Omeprazole magnesium is the most common antiulcerant in Bangladesh which are widely prescribed by the physicians for peptic ulcer & GERD. Ten national brands with reference brand of Omeprazole magnesium capsules were studied in stimulated gastric medium (pH 1.2) for first 2 hours and then in simulated intestinal medium (pH 6.8) for next 45 minutes using USP reference dissolution apparatus (Type 1 ) Among most of these locally manufactured Omeprazole brands showed compatible dissolution pattern & release kinetics compared with the reference brand. It was concluded from the study that most of the formulations were equivalent and there was no intra and inter variation between each and every formulation. 108 pp. Englisch. Nº de ref. de la librería 9783659253959

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4.

Jayanta Kishor chakrabarty, Sitesh Chandra Bachar, Sajal Kumar Saha
Editorial: LAP Lambert Academic Publishing (2013)
ISBN 10: 3659253952 ISBN 13: 9783659253959
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Descripción LAP Lambert Academic Publishing, 2013. Paperback. Estado de conservación: New. Language: English . Brand New Book. The main objective of present investigation was to study the dissolution pattern of most commercially available formulations of omeprazole in Bangladesh . Omeprazole magnesium is the most common antiulcerant in Bangladesh which are widely prescribed by the physicians for peptic ulcer GERD. Ten national brands with reference brand of Omeprazole magnesium capsules were studied in stimulated gastric medium (pH 1.2) for first 2 hours and then in simulated intestinal medium (pH 6.8) for next 45 minutes using USP reference dissolution apparatus (Type 1 ) Among most of these locally manufactured Omeprazole brands showed compatible dissolution pattern release kinetics compared with the reference brand. It was concluded from the study that most of the formulations were equivalent and there was no intra and inter variation between each and every formulation. Nº de ref. de la librería KNV9783659253959

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5.

Jayanta Kishor chakrabarty
Editorial: LAP Lambert Academic Publishing Nov 2013 (2013)
ISBN 10: 3659253952 ISBN 13: 9783659253959
Nuevos Taschenbuch Cantidad: 1
Impresión bajo demanda
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Descripción LAP Lambert Academic Publishing Nov 2013, 2013. Taschenbuch. Estado de conservación: Neu. This item is printed on demand - Print on Demand Neuware - The main objective of present investigation was to study the dissolution pattern of most commercially available formulations of omeprazole in Bangladesh . Omeprazole magnesium is the most common antiulcerant in Bangladesh which are widely prescribed by the physicians for peptic ulcer & GERD. Ten national brands with reference brand of Omeprazole magnesium capsules were studied in stimulated gastric medium (pH 1.2) for first 2 hours and then in simulated intestinal medium (pH 6.8) for next 45 minutes using USP reference dissolution apparatus (Type 1 ) Among most of these locally manufactured Omeprazole brands showed compatible dissolution pattern & release kinetics compared with the reference brand. It was concluded from the study that most of the formulations were equivalent and there was no intra and inter variation between each and every formulation. 108 pp. Englisch. Nº de ref. de la librería 9783659253959

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