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9783639131536: Mathematical Modelling of Enzymatic Reactions: Simulation and Parameter Estimation by Genetic Algorithm

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A deep and analytical understanding of the human metabolism grabbed attention of scientists from biology, medicine and pharmacy. Mathematical models of metabolic pathways offer several advances for this deep and analytical understanding due to their incompensable potential in predicting metabolic processes and anticipating appropriate interventions when required. This book concerns mathematical modelling analysis and simulation of metabolic pathways. These pathways include intracellular and extracellular compounds such as enzymes, metabolites, nucleotides and cofactors. The mathematical models are either in the form of nonlinear ordinary differential equations (ODE's) or differential algebraic equations (DAE's). These equations are composed of kinetic parameters such as kinetic rate constants, initial rates and concentrations of metabolites. In this book, an enzymatic system which includes Creatine Kinase, Hexokinase and Glucose 6-Phosphate Dehydrogenase (CK- HK-G6PDH) is modelled in the form of DAE's, solved numerically and the system parameters are estimated.

Biografía del autor

Dr. Süreyya Özö¿ür-Akyüz studied Mathematics at Middle East Technical University (METU), Turkey. She did her Msc and PhD at Institute of Applied Mathematics (IAM), METU. Dr. Özö¿ür-Akyüz is a postdoctoral researcher at Sabanc¿ University, Turkey where she is working on pattern recognition, data mining and continuous optimization.

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  • EditorialVDM Verlag Dr. Müller
  • Año de publicación2009
  • ISBN 10 3639131533
  • ISBN 13 9783639131536
  • EncuadernaciónTapa blanda
  • Número de páginas88

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Süreyya Özö ür-Akyüz
Publicado por VDM Verlag Dr. Müller, 2009
ISBN 10: 3639131533 ISBN 13: 9783639131536
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A deep and analytical understanding of the human metabolism grabbed attention of scientists from biology, medicine and pharmacy. Mathematical models of metabolic pathways offer several advances for this deep and analytical understanding due to their incompensable potential in predicting metabolic processes and anticipating appropriate interventions when required. This book concerns mathematical modelling analysis and simulation of metabolic pathways. These pathways include intracellular and extracellular compounds such as enzymes,metabolites, nucleotides and cofactors. The mathematical models are either in the form of nonlinear ordinary differential equations (ODE's) or differential algebraic equations (DAE's). These equations are composed of kinetic parameters such as kinetic rate constants, initial rates and concentrations of metabolites. In this book, an enzymatic system which includes Creatine Kinase, Hexokinase and Glucose 6-Phosphate Dehydrogenase (CK-HK-G6PDH) is modelled in the form of DAE's, solved numerically and the system parameters are estimated. 88 pp. Englisch. Nº de ref. del artículo: 9783639131536

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Süreyya Özö ür-Akyüz
Publicado por VDM Verlag Dr. Müller, 2009
ISBN 10: 3639131533 ISBN 13: 9783639131536
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Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A deep and analytical understanding of the human metabolism grabbed attention of scientists from biology, medicine and pharmacy. Mathematical models of metabolic pathways offer several advances for this deep and analytical understanding due to their incompensable potential in predicting metabolic processes and anticipating appropriate interventions when required. This book concerns mathematical modelling analysis and simulation of metabolic pathways. These pathways include intracellular and extracellular compounds such as enzymes,metabolites, nucleotides and cofactors. The mathematical models are either in the form of nonlinear ordinary differential equations (ODE's) or differential algebraic equations (DAE's). These equations are composed of kinetic parameters such as kinetic rate constants, initial rates and concentrations of metabolites. In this book, an enzymatic system which includes Creatine Kinase, Hexokinase and Glucose 6-Phosphate Dehydrogenase (CK-HK-G6PDH) is modelled in the form of DAE's, solved numerically and the system parameters are estimated. Nº de ref. del artículo: 9783639131536

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Süreyya Özögür-Akyüz
Publicado por VDM Verlag Dr. Müller, 2009
ISBN 10: 3639131533 ISBN 13: 9783639131536
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Kartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Oezoeguer-Akyuez SuereyyaDr. Suereyya Oezoeguer-Akyuez studied Mathematics at Middle East nTechnical University (METU), Turkey. She did her Msc and PhD at nInstitute of Applied Mathematics (IAM), METU. Dr. Oezoeguer-Akyuez nis a postdoctoral resea. Nº de ref. del artículo: 4960305

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Süreyya Özö¿ür-Akyüz
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Paperback. Condición: Brand New. 88 pages. 8.66x5.91x0.21 inches. In Stock. This item is printed on demand. Nº de ref. del artículo: 3639131533

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